Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.52 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.52 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11920084 | 0.83 | L3MBTL1 (0.45) | L3MBTL1KDM4ELMNAALDH1A1CYP1A2 | |
| SCHEMBL54072 | 0.78 | KMT2A (0.56) | L3MBTL1KDM4ELMNAALDH1A1CYP1A2 | |
| Benzene SCHEMBL28216395 | 0.78 | KMT2A (0.56) | L3MBTL1KDM4ELMNAALDH1A1CYP1A2 | |
| SCHEMBL1919299 | 0.78 | PLOD2 (0.60) | L3MBTL1KDM4ELMNAALDH1A1CYP1A2 | |
| SCHEMBL659602 | 0.77 | ALDH1A1 (0.61) | L3MBTL1LMNAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL863102 | 0.77 | ESR2 (0.59) | L3MBTL1KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL2064455 | 0.77 | NPC1 (0.58) | L3MBTL1LMNAALDH1A1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL27547476 | 0.77 | NPC1 (0.54) | L3MBTL1KDM4ELMNAALDH1A1CYP1A2 | |
| SCHEMBL7290567 | 0.77 | CA1 (0.54) | ALDH1A1KMT2AMAPTSMN1; SMN2TSHR | |
| SCHEMBL8399349 | 0.77 | NPC1 (0.54) | L3MBTL1KDM4ELMNAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743455-A1 | SARM1 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025012296-A1 | SARM1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-16 | — | — | WO | disclosed |