SCHEMBL119523

SCHEMBL119523

Cc1cc2sc(C)cc2s1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
PKM P14618 2/20 0.39
RXFP1 Q9HBX9 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HSD17B10 Q99714 3/20 0.37
GFER P55789 1/20 0.37
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PNMT P11086 1/20 0.31
GAA P10253 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
LMNA P02545 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13407303 0.87 ALDH1A1 (0.37) ALDH1A1PKMRXFP1NPSR1HSD17B10
SCHEMBL14479816 0.87 ALDH1A1 (0.37) ALDH1A1PKMRXFP1NPSR1HSD17B10
SCHEMBL147759 0.83 ALDH1A1 (0.34) ALDH1A1PKMRXFP1NPSR1HSD17B10
SCHEMBL18876233 0.83 ALDH1A1 (0.34) ALDH1A1PKMRXFP1NPSR1HSD17B10
SCHEMBL14227567 0.83 ALDH1A1 (0.34) ALDH1A1PKMRXFP1NPSR1HSD17B10
SCHEMBL13407304 0.79 ALDH1A1 (0.36) ALDH1A1PKMRXFP1NPSR1
SCHEMBL9980199 0.79 ALDH1A1 (0.32) ALDH1A1PKMRXFP1NPSR1
SCHEMBL18386510 0.79 ALDH1A1 (0.34) ALDH1A1PKMRXFP1NPSR1HSD17B10
SCHEMBL13407302 0.79 ESR1 (0.43) ALDH1A1HSD17B10MAPTHPGDNPC1
SCHEMBL14854116 0.79 ALDH1A1 (0.36) ALDH1A1PKMRXFP1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 684 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1715840-B1 KERATIN DYEING COMPOSITIONS CONTAINING BICYCLIC FUSED 5-5 HETEROAROMATIC DYES PROCTER & GAMBLE (US) 2008-12-03 EP claimed
US-7303590-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2007-12-04 US claimed
US-20050193502-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER, GAMBLE COMPANY, THE 2005-09-08 US claimed
US-12043749-B2 Method for producing ink composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-07-23 US disclosed
US-12043749-B2 Method for producing ink composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-07-23 US disclosed
US-20240072425-A1 AROMATIC ISOTHIOCYANATES MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
US-20240072425-A1 AROMATIC ISOTHIOCYANATES MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
US-11917839-B2 High signal-to-noise ratio photoelectric conversion element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-02-27 US disclosed
US-11917839-B2 High signal-to-noise ratio photoelectric conversion element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-02-27 US disclosed
US-20240023422-A1 COMPOSITION, FILM, ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, AND PHOTODETECTION ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-01-18 US disclosed
US-20240023422-A1 COMPOSITION, FILM, ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, AND PHOTODETECTION ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-01-18 US disclosed
US-20070179299-A1 Dioxaborines as organic n-semiconductors, process for the production of semiconductors utilizing dioxaborines, and semiconductor component, field effect transistor, and diode having a dioxaborine INFINEON TECHNOLOGIES AG 2007-08-02 US disclosed
US-20070112171-A1 Polymer having thieno[3,2-b] thiophene moieties statement regarding federally sponsored research or development XEROX CORPORATION 2007-05-17 US disclosed
US-20070073052-A1 Organic dye used in dye-sensitized solar cell REBOUND TECHNOLOGIES, INC. 2007-03-29 US disclosed
US-20070045592-A1 Process for the polymerisation of thiophene or selenophene compounds FLEXENABLE TECHNOLOGY LIMITED (GB) 2007-03-01 US disclosed
US-20070045618-A1 Organic semiconductor material, organic semiconductor element and field effect transistor using the same SANYO ELECTRIC CO., LTD. (JP) 2007-03-01 US disclosed
EP-1754736-A1 Process for the polymerisation of thiophene or selenophene derivatives Merck Patent GmbH (DE) 2007-02-21 EP disclosed
EP-1715840-A1 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF The Procter and Gamble Company (US) 2006-11-02 EP disclosed
US-20050193502-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER, GAMBLE COMPANY, THE 2005-09-08 US disclosed
WO-2005077324-A1 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2005-08-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240072425-A1 AROMATIC ISOTHIOCYANATES TRPA1, TRPC1, CRY1 ALDH1A1 1864/4885PKM 3670/4885RXFP1 2958/4885
US-20070073052-A1 Organic dye used in dye-sensitized solar cell SP1, ASPH, CCND1 ALDH1A1 56/4885PKM 2472/4885RXFP1 4722/4885
US-20070179299-A1 Dioxaborines as organic n-semiconductors, process for the production of semiconductors utilizing dioxaborines, and semiconductor component, field effect transistor, and diode having a dioxaborine NME2, DDT, DBF4 ALDH1A1 3361/4885PKM 3451/4885RXFP1 3709/4885
US-20070045618-A1 Organic semiconductor material, organic semiconductor element and field effect transistor using the same AS3MT, TST, ALK ALDH1A1 3283/4885PKM 2121/4885RXFP1 3795/4885
US-20050193502-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof KRT18, KLK5, CKMT1A; CKMT1B ALDH1A1 492/4885PKM 294/4885RXFP1 4852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.