Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | IAPP | P10997 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31501088 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAPTGS1HTT | |
| SCHEMBL13164787 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAPTGS1HTT | |
| SCHEMBL8074415 | 0.77 | MAPT (0.33) | GLATDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL8074416 | 0.77 | MAPT (0.33) | GLATDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL18662485 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAPTGS1HTT | |
| SCHEMBL18662483 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAPTGS1HTT | |
| SCHEMBL14302972 | 0.75 | IAPP (0.44) | GLATDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL6049312 | 0.75 | GLA (0.45) | GLATDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL6049311 | 0.75 | GLA (0.45) | GLATDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL10792668 | 0.73 | MAPT (0.33) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130029923-A1 | Materials and Methods for Prevention and Treatment of Viral Infections | BAGI RESEARCH LIMITED (CN) | 2013-01-31 | — | — | US | disclosed |
| US-8242171-B2 | Method for reducing the weight of a subject or inhibiting weight gain in a subject | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-08-14 | — | — | US | disclosed |
| US-7879951-B2 | Organic insulator composition, organic insulating layer including the composition, and organic thin film transistor including the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-02-01 | — | — | US | disclosed |
| US-20100316679-A1 | COMPOSITIONS FOR TREATING OR PREVENTING OBESITY AND INSULIN RESISTANCE DISORDERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100242139-A1 | XENOHORMESIS BASED COMPOSITIONS AND METHODS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-09-23 | — | — | US | disclosed |
| US-7741508-B2 | Single step green process for the preparation of substituted cinnamic esters with trans-selectivity | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-06-22 | — | — | US | disclosed |
| US-20100035885-A1 | COMPOSITIONS FOR MANIPULATING THE LIFESPAN AND STRESS RESPONSE OF CELLS AND ORGANISMS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-02-11 | — | — | US | disclosed |
| US-20090206330-A1 | Organic insulator composition, organic insulating layer including the composition, and organic thin film transistor including the same | SAMSUNG ELECTRONICS CO., LTD. | 2009-08-20 | — | — | US | disclosed |
| US-20080045742-A1 | Single step green process for the preparation of substituted cinnamic esters with trans-selectivity | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130029923-A1 | Materials and Methods for Prevention and Treatment of Viral Infections | ZC3HAV1, ZC3HAV1L, ZYX | GLA 716/4885TDP1 3945/4885ALDH1A1 2925/4885 |
| US-20100035885-A1 | COMPOSITIONS FOR MANIPULATING THE LIFESPAN AND STRESS RESPONSE OF CELLS AND ORGANISMS | SIRT1, SIRT2, FOXO3 | GLA 247/4885TDP1 281/4885ALDH1A1 4264/4885 |
| US-20100316679-A1 | COMPOSITIONS FOR TREATING OR PREVENTING OBESITY AND INSULIN RESISTANCE DISORDERS | FABP4, GPR119, SIRT1 | GLA 481/4885TDP1 4683/4885ALDH1A1 1973/4885 |
| US-20080045742-A1 | Single step green process for the preparation of substituted cinnamic esters with trans-selectivity | ADH5, CYP2E1, ADH1A | GLA 802/4885TDP1 2786/4885ALDH1A1 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.