SCHEMBL120010

SCHEMBL120010

O=c1c(OP(=O)(O)O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLH Q9Y253 8/20 0.72
KDM4E B2RXH2 5/20 0.72
MEN1 O00255 4/20 0.72
KMT2A Q03164 4/20 0.72
POLB P06746 4/20 0.72
RECQL P46063 4/20 0.72
GAA P10253 3/20 0.72
HSD17B10 Q99714 3/20 0.72
APEX1 P27695 3/20 0.72
MMP1 P03956 2/20 0.72
MAPT P10636 2/20 0.72
BLM P54132 2/20 0.72
HTT P42858 1/20 0.72
EPHX2 P34913 4/20 0.65
CYP3A4 P08684 3/20 0.65
SLCO2B1 O94956 3/20 0.65
AKR1B1 P15121 3/20 0.65
MAOA P21397 3/20 0.65
XDH P47989 3/20 0.65
USP2 O75604 2/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quercetin SCHEMBL4473370 0.96 MEN1 (0.74) POLHKDM4EMEN1KMT2APOLB
SCHEMBL119670 0.91 POLH (0.73) POLHKDM4EMEN1KMT2APOLB
SCHEMBL14786208 0.86 POLH (0.81) POLHKDM4EMEN1KMT2APOLB
SCHEMBL4286345 0.86 MEN1 (0.65) POLHKDM4EMEN1KMT2APOLB
SCHEMBL3757805 0.85 POLH (0.74) POLHKDM4EMEN1KMT2APOLB
SCHEMBL28297226 0.85 POLH (0.79) POLHKDM4EMEN1KMT2APOLB
SCHEMBL9512509 0.84 POLH (0.77) POLHKDM4EMEN1KMT2APOLB
3-O-Methylquercetin SCHEMBL29897544 0.84 POLH (1.00) POLHKDM4EMEN1KMT2APOLB
3-O-Methylquercetin SCHEMBL380558 0.84 POLH (1.00) POLHKDM4EMEN1KMT2APOLB
SCHEMBL2396323 0.83 HSD17B10 (0.66) POLHKDM4EMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118580384-A Fucoidin Process for producing phosphoric acid esters 青岛职业技术学院 2024-09-03 CN claimed
CN-105902487-A Injection pharmaceutical composition capable of improving stability of quercetin medication injection preparation 成都易创思生物科技有限公司 2016-08-31 CN claimed
CN-105241938-A Construction method and detection method of potassium ion nucleic acid aptamer photoelectrochemical sensor based on diluted magnetic semiconductor YANCHENG INST TECHNOLOGY 2016-01-13 CN claimed
US-20090325906-A1 Methods and compositions for therapeutic treatment LIMERICK BIOPHARMA, INC. 2009-12-31 US claimed
WO-2009158031-A2 METHODS AND COMPOSITIONS FOR THERAPEUTIC TREATMENT LIMERICK BIOPHARMA, INC. (US) 2009-12-30 WO claimed
WO-2009158007-A2 METHODS AND COMPOSITIONS FOR THERAPEUTIC TREATMENT LIMERICK BIOPHARMA, INC. (US) 2009-12-30 WO claimed
JP-1153695-A None JP disclosed
CN-118580384-A Fucoidin Process for producing phosphoric acid esters 青岛职业技术学院 2024-09-03 CN disclosed
CN-118580384-A Fucoidin Process for producing phosphoric acid esters 青岛职业技术学院 2024-09-03 CN disclosed
WO-2018172942-A1 QUERCETIN NANOPARTICLES THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2018-09-27 WO disclosed
WO-2018172942-A1 QUERCETIN NANOPARTICLES THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2018-09-27 WO disclosed
CN-105963247-A Preparation method of injection medicine for improving stability of quercetin medicine injection preparation 成都易创思生物科技有限公司 2016-09-28 CN disclosed
CN-105902487-A Injection pharmaceutical composition capable of improving stability of quercetin medication injection preparation 成都易创思生物科技有限公司 2016-08-31 CN disclosed
EP-2182957-A2 PHOSPHORYLATED PYRONE ANALOGS AND METHODS Limerick BioPharma, Inc. (US) 2010-05-12 EP disclosed
US-20090325906-A1 Methods and compositions for therapeutic treatment LIMERICK BIOPHARMA, INC. 2009-12-31 US disclosed
WO-2009158031-A2 METHODS AND COMPOSITIONS FOR THERAPEUTIC TREATMENT LIMERICK BIOPHARMA, INC. (US) 2009-12-30 WO disclosed
WO-2009158007-A2 METHODS AND COMPOSITIONS FOR THERAPEUTIC TREATMENT LIMERICK BIOPHARMA, INC. (US) 2009-12-30 WO disclosed
US-20090069273-A1 PHOSPHORYLATED PYRONE ANALOGS AND METHODS LIMERICK BIOPHARMA, INC. 2009-03-12 US disclosed
WO-2009018338-A2 PHOSPHORYLATED PYRONE ANALOGS AND METHODS LIMERICK BIOPHARMA, INC. (US) 2009-02-05 WO disclosed
JP-H01153695-A PRODUCTION OF RUTIN OR QUERCETIN PHOSPHORIC ACID ESTER SHOWA DENKO KK 1989-06-15 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090069273-A1 PHOSPHORYLATED PYRONE ANALOGS AND METHODS PCK1, PC, PCK2 POLH 2464/4885KDM4E 1623/4885MEN1 4072/4885
US-20090325906-A1 Methods and compositions for therapeutic treatment SLC2A1, SLC2A2, SLC2A3 POLH 3338/4885KDM4E 4285/4885MEN1 4409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.