SCHEMBL120380

SCHEMBL120380

CCCC(=O)Oc1ccc(CO)c(OC)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.48
ALDH1A1 P00352 2/20 0.48
KDM4E B2RXH2 1/20 0.48
GLA P06280 1/20 0.48
GAA P10253 1/20 0.48
BCL9 O00512 1/20 0.46
CTNNB1 P35222 1/20 0.46
MAPT P10636 4/20 0.44
LMNA P02545 1/20 0.44
HTT P42858 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PDGFRB P09619 1/20 0.41
PDGFRA P16234 1/20 0.41
CA2 P00918 2/20 0.41
APLNR P35414 1/20 0.41
CNR1 P21554 2/20 0.40
PDCD1 Q15116 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
ALOX15 P16050 1/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27529821 0.86 CNR1 (0.39) KMT2AALDH1A1APLNRCNR1PDCD1
SCHEMBL16929988 0.84 CA2 (0.50) KMT2AALDH1A1KDM4EGLAGAA
SCHEMBL7095189 0.83 KDM4E (0.51) KMT2AKDM4EGLAGAAMAPT
SCHEMBL8838326 0.82 KDM4E (0.49) KMT2AALDH1A1KDM4EGLAGAA
SCHEMBL26093135 0.82 ALDH1A1 (0.53) KMT2AALDH1A1KDM4EGLAGAA
SCHEMBL10801524 0.79 BCL9 (0.48) KMT2AALDH1A1KDM4EGLAGAA
SCHEMBL7755696 0.78 KMT2A (0.48) KMT2AALDH1A1KDM4EGLAGAA
SCHEMBL7656402 0.78 ALOX15 (0.48) KMT2AALDH1A1KDM4EGLAGAA
SCHEMBL298382 0.77 AR (0.50) KMT2AALDH1A1KDM4EGLAGAA
SCHEMBL238087 0.77 APLNR (0.63) KMT2AALDH1A1KDM4EMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4610268-A1 CELL-MEMBRANE-PERMEABLE PEPTIDE FOR CONJUGATION AGC INC. (JP) 2025-09-03 EP disclosed
CN-119431135-B Preparation method of 4- (4-hydroxymethyl-3-methoxyphenoxy) butyric acid 安徽昊帆生物有限公司 2025-04-08 CN disclosed
CN-119431135-A Preparation method of 4- (4-hydroxymethyl-3-methoxyphenoxy) butyric acid 安徽昊帆生物有限公司 2025-02-14 CN disclosed
EP-3995486-A1 PEPTIDE AND METHOD FOR MANUFACTURING SAME AGC INC. (JP) 2022-05-11 EP disclosed
US-20220119440-A1 PEPTIDE AND METHOD FOR MANUFACTURING SAME AGC Inc. (JP) 2022-04-21 US disclosed
US-10905769-B2 Peptide and peptide mimetic binding antagonists of polo-like kinase 1 polo box domain and methods of use THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2021-02-02 US disclosed
EP-3215116-B1 A HIGH MOLECULAR WEIGHT BIODEGRADABLE GELATIN-DOXORUBICIN CONJUGATE UNIV OF THE SCIENCES IN PHILADELPHIA (US) 2020-09-30 EP disclosed
US-10358470-B2 Glycosylated polypeptide and pharmaceutical composition containing same GLYTECH, INC. (JP) 2019-07-23 US disclosed
US-10265413-B2 High molecular weight biodegradable gelatin-doxorubicin conjugate UNIVERSITY OF THE SCIENCES IN PHILADELPHIA (US) 2019-04-23 US disclosed
US-20180296686-A1 PEPTIDE AND PEPTIDE MIMETIC BINDING ANTAGONISTS OF POLO-LIKE KINASE 1 POLO BOX DOMAIN AND METHODS OF USE THE US DEPARTMENT OF HEALTH &HUMAN SERVICES (US) 2018-10-18 US disclosed
US-20030125516-A1 Methods and compositions for peptide synthesis TRIMERIS, INC. 2003-07-03 US disclosed
US-6469136-B1 SOLID PHASE/LIQUID PHASE SYNTHESIS; PURIFICATION; AMINO ACID SEQUENCES TRIMERIS, INC. 2002-10-22 US disclosed
WO-2001034635-A9 METHODS AND COMPOSITIONS FOR PEPTIDE SYNTHESIS TRIMERIS INC (US) 2002-08-01 WO disclosed
EP-1071442-A4 METHODS AND COMPOSITIONS FOR PEPTIDE SYNTHESIS TRIMERIS INC (US) 2002-06-05 EP disclosed
US-6281331-B1 A SET OF T-20 PEPTIDE FRAGMENTS SYNTHESIZED BY SOLID AND LIQUID PHASE SYNTHESIS; FOR LARGE SCALE PRODUCTION FOR USE IN THERAPEUTICS OF HUMAN IMMUNODEFICIENCY VIRUS-1 TRIMERIS, INC. 2001-08-28 US disclosed
CN-1303299-A Method and compositions for peptide synthesis TRIMERIS INC (US) 2001-07-11 CN disclosed
WO-2001034635-A2 METHODS AND COMPOSITIONS FOR PEPTIDE SYNTHESIS TRIMERIS, INC. (US) 2001-05-17 WO disclosed
EP-1071442-A1 METHODS AND COMPOSITIONS FOR PEPTIDE SYNTHESIS TRIMERIS INC. (US) 2001-01-31 EP disclosed
US-6015881-A COUPLING TOGETHER SPECIFIC SIDE-CHAIN PROTECTED PEPTIDE FRAGMENTS, DEPROTECTING AMINO TERMINUS, REACTING WITH ANOTHER PROTECTED PEPTIDE, MODIFYING AMINO TERMINUS TO ACETYL GROUP, DEPROTECTING SIDE-CHAINS; HIGH PURITY; GREATER LOAD TRIMERIS, INC. 2000-01-18 US disclosed
WO-1999048513-A1 METHODS AND COMPOSITIONS FOR PEPTIDE SYNTHESIS TRIMERIS, INC. (US) 1999-09-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10358470-B2 Glycosylated polypeptide and pharmaceutical composition containing same IFNG, IFNAR1, IAPP KMT2A 4694/4885ALDH1A1 3871/4885KDM4E 4841/4885
US-10905769-B2 Peptide and peptide mimetic binding antagonists of polo-like kinase 1 polo box domain and methods of use PLK1, POLR1E, POLK KMT2A 1885/4885ALDH1A1 4834/4885KDM4E 2771/4885
US-20180296686-A1 PEPTIDE AND PEPTIDE MIMETIC BINDING ANTAGONISTS OF POLO-LIKE KINASE 1 POLO BOX DOMAIN AND METHODS OF USE PLK1, POLR1E, POLK KMT2A 1885/4885ALDH1A1 4834/4885KDM4E 2771/4885
US-10265413-B2 High molecular weight biodegradable gelatin-doxorubicin conjugate MMP2, DNASE1L3, DNASE1 KMT2A 4101/4885ALDH1A1 620/4885KDM4E 3654/4885
US-20220119440-A1 PEPTIDE AND METHOD FOR MANUFACTURING SAME VIP, RFC2, QRFPR KMT2A 2571/4885ALDH1A1 4069/4885KDM4E 2839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.