SCHEMBL1204321

SCHEMBL1204321

COc1cc(F)ccc1Br

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 3/20 0.46
MAPT P10636 2/20 0.46
HTR2A P28223 1/20 0.43
ALDH1A1 P00352 2/20 0.42
NFE2L2 Q16236 1/20 0.41
MAPK1 P28482 1/20 0.41
FFAR1 O14842 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
POLB P06746 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PDGFRB P09619 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29712244 1.00 AMY1A (0.46) AMY1AMAPTHTR2AALDH1A1NFE2L2
SCHEMBL14830711 0.98 AMY1A (0.45) AMY1AMAPTHTR2AALDH1A1NFE2L2
SCHEMBL22505897 0.85 FFAR1 (0.38) AMY1AMAPTHTR2AALDH1A1NFE2L2
SCHEMBL23259236 0.84 KDM4E (0.40) AMY1AMAPTALDH1A1NFE2L2FFAR1
SCHEMBL504965 0.82 ALDH1A1 (0.52) AMY1AMAPTHTR2AALDH1A1NFE2L2
SCHEMBL14482753 0.82 ALDH1A1 (0.52) AMY1AMAPTHTR2AALDH1A1NFE2L2
SCHEMBL29849146 0.82 ALDH1A1 (0.52) AMY1AMAPTHTR2AALDH1A1NFE2L2
SCHEMBL3823791 0.80 MAPT (0.50) AMY1AMAPTHTR2AALDH1A1NFE2L2
SCHEMBL19198177 0.79 NFE2L2 (0.72) NFE2L2
SCHEMBL15202541 0.79 FYN (0.51) MAPTALDH1A1MEN1KMT2APDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 530 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109810571-A Inorganic nano material prints ink and its preparation method and application TCL集团股份有限公司 2019-05-28 CN claimed
CN-106083536-B A kind of preparation method of Ansai Qu key intermediate 浙江永太科技股份有限公司 2018-10-30 CN claimed
CN-106083536-A A kind of preparation method of the bent key intermediate in Ansai 浙江永太科技股份有限公司 2016-11-09 CN claimed
US-20150344486-A1 PYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS CYCLACEL LIMITED (GB) 2015-12-03 US claimed
EP-4747260-A1 MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. Hoffmann-La Roche AG (CH) 2026-05-27 EP disclosed
EP-4739670-A1 MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. Hoffmann-La Roche AG (CH) 2026-05-13 EP disclosed
WO-2026090477-A1 HELICASE INHIBITORS AND USES THEREOF KIMIA THERAPEUTICS, INC. (US) 2026-04-30 WO disclosed
US-12600711-B2 Triazacyclododecansulfonamide (TCD)-based protein secretion inhibitors KEZAR LIFE SCIENCES, INC. (US) 2026-04-14 US disclosed
EP-4466266-B1 FUSED HETEROCYCLES AS 5-HT2A RECEPTOR AGONISTS TRANSNEURAL THERAPEUTICS INC (US) 2026-04-08 EP disclosed
US-20260070927-A1 INDAZOLE MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE HOFFMANN-LA ROCHE INC. (US) 2026-03-12 US disclosed
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 US disclosed
US-12522619-B2 Inhibitors of complement factors and uses thereof ANNEXON, INC. (US) 2026-01-13 US disclosed
US-5688808-A Steroid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-11-18 US disclosed
US-5688810-A Steroid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-11-18 US disclosed
EP-0800519-A1 STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS LIGAND PHARMACEUTICALS, INC. (US) 1997-10-15 EP disclosed
WO-1996019458-A2 STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS LIGAND PHARMACEUTICALS INCORPORATED (US) 1996-06-27 WO disclosed
EP-0193055-B1 ANTITUMORALS(1,2-DIPHENYL-ETHYLENE DIAMINE)-PLATINUM (II) COMPLEXES ASTA Pharma AG (DE) 1990-05-16 EP disclosed
US-4730068-A SPECIAL EFFECT ON BREAST CANCER ASTA-WERKE AKTIENGESELLSCHAFT (DE) 1988-03-08 US disclosed
CN-86100815-A The preparation method who suppresses (1, the 2-diphenyl ethylene diamine)-platinum (II) complex compound of tumour 1986-11-26 CN disclosed
EP-0193055-A1 Antitumorals(1,2-diphenyl-ethylene diamine)-platinum (II) complexes ASTA Pharma AG (DE) 1986-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B AMY1A 1206/4885MAPT 2629/4885HTR2A 678/4885
US-20260070927-A1 INDAZOLE MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE MALT1, CCR1, CCR6 AMY1A 641/4885MAPT 4693/4885HTR2A 3728/4885
US-20150344486-A1 PYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS DCK, DTYMK, TK1 AMY1A 4858/4885MAPT 2501/4885HTR2A 3888/4885
US-12600711-B2 Triazacyclododecansulfonamide (TCD)-based protein secretion inhibitors CD274, CD40, ICOS AMY1A 4151/4885MAPT 2305/4885HTR2A 2896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.