SCHEMBL12048461

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12048334	0.97	SCN9A (0.46)	HRH3ABCG2SCN9AMEN1NPC1
	SCHEMBL12048050	0.97	ABCG2 (0.47)	HRH3ABCG2SCN9AMEN1NPC1
	SCHEMBL12048561	0.97	ABCG2 (0.47)	HRH3ABCG2SCN9AMEN1NPC1
	SCHEMBL12047982	0.96	ABCG2 (0.43)	HRH3ABCG2SCN9AMEN1NPC1
	SCHEMBL12047831	0.93	ABCG2 (0.44)	HRH3ABCG2SCN9AMEN1NPC1
	SCHEMBL23204403	0.93	HRH3 (0.43)	HRH3MEN1NPC1RAB9AKMT2A
	SCHEMBL12048605	0.92	ABCG2 (0.44)	HRH3ABCG2SCN9AKDM1AGABRA1
	SCHEMBL12048109	0.91	ABCG2 (0.44)	HRH3ABCG2SCN9AMEN1NPC1
	SCHEMBL12048462	0.89	KDM4C (0.41)	HRH3ABCG2SCN9AMEN1KMT2A
	SCHEMBL12048333	0.88	KDM4C (0.40)	HRH3ABCG2SCN9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.