SCHEMBL1205134

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4506889	0.83	AOC3 (0.46)	AOC3MAPTGAAALDH1A1KDM4E
	SCHEMBL3068361	0.74	GRIK1 (0.49)	AOC3MAPTGAAALDH1A1KDM4E
	SCHEMBL927313	0.72	AOC3 (0.46)	AOC3MAPTGAAALDH1A1KDM4E
	SCHEMBL5493171	0.72	KDM4E (0.51)	AOC3MAPTGAAALDH1A1KDM4E
	SCHEMBL3082016	0.72	GRIK1 (0.45)	AOC3MAPTGAAALDH1A1KDM4E
	SCHEMBL4506884	0.72	GRIK1 (0.45)	AOC3MAPTGAAALDH1A1KDM4E
	SCHEMBL3476327	0.72	AOC3 (0.54)	AOC3MAPTGAAALDH1A1KDM4E
	SCHEMBL30287355	0.72	AOC3 (0.54)	AOC3MAPTGAAALDH1A1KDM4E
	SCHEMBL31232953	0.72	FLT3 (0.48)	AOC3MAPTGAAALDH1A1KDM4E
	SCHEMBL10826335	0.72	FLT3 (0.48)	AOC3MAPTGAAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.