Sorbitololeic Acid

Sorbitololeic Acid

SCHEMBL1207256

CCCCCCCC/C=C\CCCCCCCC(=O)OCC(O)C(O)C(O)C(O)CO

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.73
PRKCA P17252 2/20 0.66
PRKCE Q02156 1/20 0.66
PRKCQ Q04759 1/20 0.66
PRKCD Q05655 1/20 0.66
FAAH O00519 2/20 0.62
KDM4E B2RXH2 1/20 0.58
DUSP3 P51452 1/20 0.58
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
LMNA P02545 1/20 0.58
LPAR1 Q92633 7/20 0.58
LPAR4 Q99677 3/20 0.58
LPAR2 Q9HBW0 3/20 0.58
LPAR3 Q9UBY5 3/20 0.58
ENPP2 Q13822 2/20 0.58
LPAR5 Q9H1C0 2/20 0.58
CES2 O00748 1/20 0.58
LPAR6 P43657 1/20 0.58
TRPV1 Q8NER1 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sorbitololeic Acid SCHEMBL3268606 1.00 DGKA (0.73) DGKAPRKCAPRKCEPRKCQPRKCD
Sorbitololeic Acid SCHEMBL30331597 1.00 DGKA (0.73) DGKAPRKCAPRKCEPRKCQPRKCD
Sorbitololeic Acid SCHEMBL41613 1.00 DGKA (0.73) DGKAPRKCAPRKCEPRKCQPRKCD
SCHEMBL11046699 0.97 DGKA (0.73) DGKAPRKCAPRKCEPRKCQPRKCD
SCHEMBL1795164 0.97 DGKA (0.73) DGKAPRKCAPRKCEPRKCQPRKCD
SCHEMBL6149779 0.96 FAAH (0.69) DGKAPRKCAPRKCEPRKCQPRKCD
Sorbitololeic Acid SCHEMBL11211814 0.94 DGKA (0.69) DGKAPRKCAPRKCEPRKCQPRKCD
Sorbitololeic Acid SCHEMBL6112163 0.94 DGKA (0.65) DGKAPRKCAPRKCEPRKCQPRKCD
Glyceryl Monooleate SCHEMBL27704769 0.92 DGKA (0.87) DGKAPRKCAPRKCEPRKCQPRKCD
SCHEMBL8188858 0.92 DGKA (0.77) DGKAPRKCAPRKCEPRKCQPRKCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230149309-A1 COMPOSITION COMPRISING ANTIMICROBIAL AGENT AND ITS USES SHARED VISION TECHNOLOGY LTD. (IE) 2023-05-18 US disclosed
EP-4117633-A1 COMPOSITION COMPRISING ANTIMICROBIAL AGENT AND ITS USES SHARED VISION TECHNOLOGY LTD. (IE) 2023-01-18 EP disclosed
WO-2021191462-A1 COMPOSITION COMPRISING ANTIMICROBIAL AGENT AND ITS USES SHARED VISION TECHNOLOGY LTD. (IE) 2021-09-30 WO disclosed
US-9687551-B2 Compositions comprising lecithin oils and NSAIDs for protecting the gastrointestinal tract and providing enhanced therapeutic activity THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2017-06-27 US disclosed
US-20160271255-A1 COMPOSITIONS COMPRISING LECITHIN OILS AND NSAIDS FOR PROTECTING THE GASTROINTESTINAL TRACT AND PROVIDING ENHANCED THERAPEUTIC ACTIVITY THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2016-09-22 US disclosed
US-20160220679-A1 COMPOSITIONS COMPRISING LECITHIN OILS AND NSAIDS FOR PROTECTING THE GASTROINTESTINAL TRACT AND PROVIDING ENHANCED THERAPEUTIC ACTIVITY UNIV TEXAS (US) 2016-08-04 US disclosed
US-9351984-B2 Compositions comprising lecithin oils and NSAIDs for protecting the gastrointestinal tract and providing enhanced therapeutic activity THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2016-05-31 US disclosed
US-9101637-B2 Methods of treating inflammation with compositions comprising lecithin oils and NSAIDS for protecting the gastrointestinal tract and providing enhanced therapeutic activity THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2015-08-11 US disclosed
US-20150011507-A1 COMPOSITIONS COMPRISING LECITHIN OILS AND NSAIDS FOR PROTECTING THE GASTROINTESTINAL TRACT AND PROVIDING ENHANCED THERAPEUTIC ACTIVITY THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2015-01-08 US disclosed
US-8911752-B2 Methods of making compositions comprising lecithin oils and NSAIDS for protecting the gastrointestinal tract and providing enhanced therapeutic activity THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-12-16 US disclosed
US-20110065677-A1 Methods of Treating Inflammation with Compositions Comprising Lecithin Oils and NSAIDS for Protecting the Gastrointestinal Tract and Providing Enhanced Therapeutic Activity THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2011-03-17 US disclosed
US-20110034568-A1 Compositions comprising lecithin oils and NSAIDS for protecting the gastrointestinal tract and providing enhanced therapeutic activity THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2011-02-10 US disclosed
US-20100173876-A1 OIL-BASED NSAID COMPOSITIONS AND METHODS FOR MAKING AND USING SAME THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-07-08 US disclosed
EP-1343529-B1 NSAID FORMULATIONS COMPRISING LECITHIN OILS FOR PROTECTING THE GASTROINTESTINAL TRACT AND PROVIDING ENHANCED THERAPEUTIC ACTIVITY UNIV TEXAS (US) 2008-11-19 EP disclosed
EP-1804766-A2 PURIFIED PHOSPHOLIPID-NON-STEROIDAL ANTI-INFLAMMATORY DRUG ASSOCIATED COMPOSITIONS AND METHODS FOR PREPARING AND USING SAME THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2007-07-11 EP disclosed
WO-2006044377-A2 PURIFIED PHOSPHOLIPID-NON-STEROIDAL ANTI-INFLAMMATORY DRUG ASSOCIATED COMPOSITIONS AND METHODS FOR PREPARING AND USING SAME THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2006-04-27 WO disclosed
US-20060078574-A1 Purified phospholipid-non-steroidal anti-inflammatory drug associated compositions and methods for preparing and using same THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2006-04-13 US disclosed
US-20040077604-A1 Reducing toxicity of nonsteroidal antiinflammatory drugs (NSAIDs) THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2004-04-22 US disclosed
EP-1343529-A2 NSAID FORMULATIONS COMPRISING LECITHIN OILS FOR PROTECTING THE GASTROINTESTINAL TRACT AND PROVIDING ENHANCED THERAPEUTIC ACTIVITY The Board of Regents, The University of Texas System (US) 2003-09-17 EP disclosed
WO-2002085414-A2 NSAID FORMULATIONS COMPRISING LECITHIN OILS FOR PROTECTING THE GASTROINTESTINAL TRACT AND PROVIDING ENHANCED THERAPEUTIC ACTIVITY THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2002-10-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060078574-A1 Purified phospholipid-non-steroidal anti-inflammatory drug associated compositions and methods for preparing and using same PHOSPHO1, PLTP, PLA2G7 DGKA 1119/4885PRKCA 3105/4885PRKCE 3011/4885
US-20100173876-A1 OIL-BASED NSAID COMPOSITIONS AND METHODS FOR MAKING AND USING SAME ALOX5, ALOX15, PTGES DGKA 412/4885PRKCA 1995/4885PRKCE 1330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.