Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBX7 | O95931 | 2/20 | 0.55 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.55 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.55 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12124515 | 0.86 | — | — | |
| SCHEMBL12124510 | 0.84 | — | — | |
| SCHEMBL12124405 | 0.84 | — | — | |
| SCHEMBL12124511 | 0.83 | — | — | |
| SCHEMBL12124415 | 0.83 | — | — | |
| SCHEMBL12124439 | 0.82 | ALDH1A1 (0.47) | — | |
| SCHEMBL14722754 | 0.78 | CDYL (0.66) | CBX7CDYL2CDYLCDY1; CDY1B | |
| SCHEMBL4386342 | 0.76 | ALDH1A1 (0.75) | CBX7CDYL2CDYLCDY1; CDY1B | |
| SCHEMBL4379269 | 0.75 | ALDH1A1 (0.73) | CBX7CDYL2CDYLCDY1; CDY1B | |
| SCHEMBL12124449 | 0.74 | GAA (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102204-B1 | HIGHLY SELECTIVE SIGMA 1 RECEPTOR LIGANDS AND RADIOLIGANDS AS PROBES IN NOCICEPTIVE PROCESSING AND THE PATHOPHYSIOLOGICAL STUDY OF MEMORY DEFICITS AND COGNITIVE DISORDERS | THE UNIV OF MISSISSIPPI (US) | 2021-05-05 | — | — | EP | disclosed |
| US-9724435-B2 | Highly selective sigma receptor ligands and radioligands as probes in nociceptive processing and the pathphysiological study of memory deficits and cognitive disorders | THE UNIVERSITY OF MISSISSIPPI (US) | 2017-08-08 | — | — | US | disclosed |
| US-9724435-B2 | Highly selective sigma receptor ligands and radioligands as probes in nociceptive processing and the pathphysiological study of memory deficits and cognitive disorders | THE UNIVERSITY OF MISSISSIPPI (US) | 2017-08-08 | — | — | US | disclosed |
| US-9604926-B2 | Highly selective sigma receptor radioligands | THE UNIVERSITY OF MISSISSIPPI (US) | 2017-03-28 | — | — | US | disclosed |
| US-9604926-B2 | Highly selective sigma receptor radioligands | THE UNIVERSITY OF MISSISSIPPI (US) | 2017-03-28 | — | — | US | disclosed |
| US-20140328755-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS AND RADIOLIGANDS AS PROBES IN NOCICEPTIVE PROCESSING AND THE PATHPHYSIOLOGICAL STUDY OF MEMORY DEFICITS AND COGNITIVE DISORDERS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2014-11-06 | — | — | US | disclosed |
| US-20140328755-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS AND RADIOLIGANDS AS PROBES IN NOCICEPTIVE PROCESSING AND THE PATHPHYSIOLOGICAL STUDY OF MEMORY DEFICITS AND COGNITIVE DISORDERS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2014-11-06 | — | — | US | disclosed |
| US-20140315919-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS | UNIV MISSISSIPPI (US) | 2014-10-23 | — | — | US | disclosed |
| US-20140315919-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS | UNIV MISSISSIPPI (US) | 2014-10-23 | — | — | US | disclosed |
| US-8809381-B2 | Highly selective sigma receptor ligands | THE UNIVERSITY OF MISSISSIPPI (US) | 2014-08-19 | — | — | US | disclosed |
| US-8809381-B2 | Highly selective sigma receptor ligands | THE UNIVERSITY OF MISSISSIPPI (US) | 2014-08-19 | — | — | US | disclosed |
| US-20110280804-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR RADIOLIGANDS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-11-17 | — | — | US | disclosed |
| US-20110280804-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR RADIOLIGANDS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-11-17 | — | — | US | disclosed |
| US-20110195955-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS | L'UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2011-08-11 | — | — | US | disclosed |
| US-20110195955-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS | L'UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2011-08-11 | — | — | US | disclosed |
| US-20100329978-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS | UNIVERSITY OF MISSISSIPPI (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100329978-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS | UNIVERSITY OF MISSISSIPPI (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100329978-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS | SIGMAR1, OPRL1, CNR1 | CBX7 2301/4885CDYL2 2648/4885CDYL 1756/4885 |
| US-20140315919-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS | SIGMAR1, OPRD1, OPRM1 | CBX7 2777/4885CDYL2 2602/4885CDYL 1769/4885 |
| US-20110195955-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS | SIGMAR1, OPRD1, OPRM1 | CBX7 2777/4885CDYL2 2602/4885CDYL 1769/4885 |
| US-20140328755-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS AND RADIOLIGANDS AS PROBES IN NOCICEPTIVE PROCESSING AND THE PATHPHYSIOLOGICAL STUDY OF MEMORY DEFICITS AND COGNITIVE DISORDERS | SIGMAR1, OPRL1, OPRK1 | CBX7 4730/4885CDYL2 4486/4885CDYL 4592/4885 |
| US-20110280804-A1 | HIGHLY SELECTIVE SIGMA RECEPTOR RADIOLIGANDS | SIGMAR1, MSR1, TMEM97 | CBX7 1773/4885CDYL2 2565/4885CDYL 1335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.