SCHEMBL12129756

SCHEMBL12129756

CCc1ccc(-c2ccc(Cl)cc2Cl)cc1C1=C(OC(C)=O)C(C)(C)OC(C)(C)C1=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SRD5A2 P31213 1/20 0.35
▸ EDNRB P24530 1/20 0.35
▸ EDNRA P25101 1/20 0.35
▸ NPC1 O15118 1/20 0.34
▸ POLB P06746 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ PTGS2 P35354 1/20 0.34
▸ MARS1 P56192 2/20 0.33
▸ GAA P10253 1/20 0.32
▸ CNR1 P21554 6/20 0.32
▸ CNR2 P34972 4/20 0.32
▸ P2RX7 Q99572 1/20 0.32
▸ CYP3A4 P08684 1/20 0.31
▸ CYP2C9 P11712 1/20 0.31
▸ ABCB11 O95342 1/20 0.31
▸ GCG P01275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29435260 1.00 SRD5A2 (0.35) SRD5A2EDNRBEDNRANPC1POLB
SCHEMBL29643042 0.93 EDNRB (0.37) SRD5A2EDNRBEDNRANPC1POLB
SCHEMBL15800880 0.93 EDNRB (0.37) SRD5A2EDNRBEDNRANPC1POLB
SCHEMBL15273862 0.91 MAOB (0.34) —
SCHEMBL12129754 0.91 EDNRB (0.34) SRD5A2EDNRBEDNRANPC1POLB
SCHEMBL29391260 0.90 CTSA (0.33) GCGR
SCHEMBL15484450 0.90 CTSA (0.33) GCGR
SCHEMBL12129764 0.90 GAA (0.35) SRD5A2EDNRBEDNRANPC1POLB
SCHEMBL31127713 0.90 GAA (0.35) SRD5A2EDNRBEDNRANPC1POLB
SCHEMBL12129729 0.90 PGR (0.33) EDNRBEDNRAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 420 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260007133-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS BASF SE (DE) 2026-01-08 — — US claimed
US-12376586-B2 Microcapsules comprising cinmethyln in the core and a polyurea derived from diphenylmethane diisocyanate or an oligomer thereof BASF Agro B.V. (NL) 2025-08-05 — — US claimed
EP-3568016-B1 MICROCAPSULES COMPRISING CINMETHYLIN IN THE CORE AND A POLYUREA DERIVED FROM DIPHENYLMETHANE DIISOCYANATE OR AN OLIGOMER THEREOF BASF AGRO BV (NL) 2024-07-17 — — EP claimed
WO-2024012905-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS BASF SE (DE) 2024-01-18 — — WO claimed
US-11839214-B2 Fungicidal mixture comprising substituted pyridines BASF SE (DE) 2023-12-12 — — US claimed
EP-3957176-A1 METHOD FOR CONTROLLING HERBICIDE RESISTANT OR TOLERANT WEEDS, HERBICIDAL COMPOSITION AND METHOD FOR CONTROLLING UNDESIRABLE VEGETATION BASF Agro B.V. (NL) 2022-02-23 — — EP claimed
US-20210145003-A1 MIXTURES COMPRISING A HERBICIDE AND A NITRIFICATION INHIBITOR SUCH AS 2-(3,4-DIMETHYL-1H-PYRAZOL-1-YL)SUCCINIC ACID (DMPSA) OR 3,4-DIMETHYL PYRAZOLIUM GLOCOLATE (DMPG) BASF SE (DE) 2021-05-20 — — US claimed
US-20210127674-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2021-05-06 — — US claimed
US-20210084902-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED 3-PHENYL-5-(TRIFLUOROMETHYL)-1,2,4-OXADIAZOLES BASF SE (DE) 2021-03-25 — — US claimed
CN-110914222-A Mixtures comprising herbicides and nitrification inhibitors, such as 2- (3, 4-dimethyl-1H-pyrazol-1-yl) succinic acid (DMPSA) or 3, 4-dimethylpyrazolium glycolate (DMPG) 巴斯夫欧洲公司 2020-03-24 — — CN claimed
US-20190110480-A1 MIXTURES AND COMPOSITIONS COMPRISING PAENIBACILLUS STRAINS OR FUSARICIDINS AND CHEMICAL PESTICIDES BASF SE (DE) 2019-04-18 — — US claimed
US-20190098899-A1 FUNGICIDAL MIXTURES III COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2019-04-04 — — US claimed
US-20180368411-A1 METHOD FOR CONTROLLING HERBICIDE RESISTANT OR TOLERANT WEEDS BASF SE (DE) 2018-12-27 — — US claimed
US-9999222-B2 Herbicidal combination comprising azines BASF SE (DE) 2018-06-19 — — US claimed
EP-3205208-A1 MIXTURES AND COMPOSITIONS COMPRISING PAENIBACILLUS STRAINS OR FUSARICIDINS AND CHEMICAL PESTICIDES BASF SE (DE) 2017-08-16 — — EP claimed
EP-3133920-A1 HERBICIDAL COMBINATION COMPRISING AZINES BASF SE (DE) 2017-03-01 — — EP claimed
US-20170042154-A1 HERBICIDAL COMBINATION COMPRISING AZINES BASF SE (DE) 2017-02-16 — — US claimed
US-20150342193-A1 Herbicidal Composition BASF SE (DE) 2015-12-03 — — US claimed
WO-2015162164-A1 HERBICIDAL COMBINATION COMPRISING AZINES BASF SE (DE) 2015-10-29 — — WO claimed
WO-2014102069-A1 HERBICIDAL COMPOSITION BASF SE (DE) 2014-07-03 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150342193-A1 Herbicidal Composition DDT, AS3MT, ACHE SRD5A2 1505/4885EDNRB 3378/4885EDNRA 3512/4885
US-11839214-B2 Fungicidal mixture comprising substituted pyridines ME1, DPM1, TH SRD5A2 1153/4885EDNRB 3894/4885EDNRA 3916/4885
US-20210127674-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES ME1, DPM1, TH SRD5A2 1153/4885EDNRB 3894/4885EDNRA 3916/4885
US-20210145003-A1 MIXTURES COMPRISING A HERBICIDE AND A NITRIFICATION INHIBITOR SUCH AS 2-(3,4-DIMETHYL-1H-PYRAZOL-1-YL)SUCCINIC ACID (DMPSA) OR 3,4-DIMETHYL PYRAZOLIUM GLOCOLATE (DMPG) GLO1, DDT, GMDS SRD5A2 3016/4885EDNRB 3147/4885EDNRA 2097/4885
US-20210084902-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED 3-PHENYL-5-(TRIFLUOROMETHYL)-1,2,4-OXADIAZOLES TH, CASP3, PIK3C3 SRD5A2 395/4885EDNRB 4498/4885EDNRA 4245/4885
US-20260007133-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS CBR3, CBR1, DDT SRD5A2 909/4885EDNRB 3970/4885EDNRA 4024/4885
US-20180368411-A1 METHOD FOR CONTROLLING HERBICIDE RESISTANT OR TOLERANT WEEDS CYP8B1, DDT, NOTUM SRD5A2 985/4885EDNRB 1561/4885EDNRA 2787/4885
US-20170042154-A1 HERBICIDAL COMBINATION COMPRISING AZINES CBR3, CBR1, DDT SRD5A2 1127/4885EDNRB 1682/4885EDNRA 1402/4885
US-20190110480-A1 MIXTURES AND COMPOSITIONS COMPRISING PAENIBACILLUS STRAINS OR FUSARICIDINS AND CHEMICAL PESTICIDES PFAS, PEF1, PGLS SRD5A2 3483/4885EDNRB 3627/4885EDNRA 4474/4885
US-12376586-B2 Microcapsules comprising cinmethyln in the core and a polyurea derived from diphenylmethane diisocyanate or an oligomer thereof NCL, PNN, DBN1 SRD5A2 4567/4885EDNRB 1783/4885EDNRA 1203/4885
US-20190098899-A1 FUNGICIDAL MIXTURES III COMPRISING STROBILURIN-TYPE FUNGICIDES DDT, SNX3, SFXN3 SRD5A2 970/4885EDNRB 4387/4885EDNRA 4564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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