Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.40 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.40 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.40 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.40 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30423475 | 0.85 | TDP1 (0.54) | TDP1NR1H2NR1H3ASAH1CES1 | |
| SCHEMBL29257418 | 0.85 | TDP1 (0.54) | TDP1NR1H2NR1H3ASAH1CES1 | |
| Hydrochloric Acid SCHEMBL30694219 | 0.84 | TDP1 (0.53) | TDP1NR1H2NR1H3ASAH1CES1 | |
| SCHEMBL5574641 | 0.79 | ALDH1A1 (0.49) | TDP1POLBCYP2D6 | |
| SCHEMBL12197551 | 0.79 | CDC25A (0.43) | MGLLNR1H2NR1H3ASAH1CES1 | |
| SCHEMBL12197535 | 0.79 | CDC25A (0.43) | MGLLNR1H2NR1H3ASAH1CES1 | |
| SCHEMBL8732975 | 0.78 | TDP1 (0.61) | TDP1POLBCYP2D6 | |
| SCHEMBL2359680 | 0.77 | MGLL (0.50) | MGLLNR1H2NR1H3ASAH1CES1 | |
| SCHEMBL8008712 | 0.77 | MGLL (0.62) | TDP1MGLLCES1CDC25AFAAH | |
| SCHEMBL2359683 | 0.77 | MGLL (0.50) | MGLLNR1H2NR1H3ASAH1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571591-B1 | FUNCTIONALIZED SUBSTRATES WITH AROMATIC STACKING PROPERTIES | DIONEX CORP (US) | 2017-08-02 | — | — | EP | disclosed |
| US-9144756-B2 | Functionalized substrates with aromatic stacking properties | DIONEX CORPORATION (US) | 2015-09-29 | — | — | US | disclosed |
| US-20110284465-A1 | FUNCTIONALIZED SUBSTRATES WITH AROMATIC STACKING PROPERTIES | DIONEX CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110284465-A1 | FUNCTIONALIZED SUBSTRATES WITH AROMATIC STACKING PROPERTIES | SRMS, STUB1, SPEN | TDP1 2374/4885MGLL 3329/4885NR1H2 2507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.