SCHEMBL12142007

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26684790	0.91	GLS (0.44)	TRPV1RIPK1GLSDPP4DPP8
	SCHEMBL14094520	0.81	NPC1 (0.52)	TRPV1RIPK1SLC6A7NPY1RNPC1
	SCHEMBL25059133	0.81	TRPV1 (0.43)	TRPV1RIPK1GLSSLC6A7NPY1R
	SCHEMBL12844313	0.81	RIPK1 (0.43)	TRPV1RIPK1GLSSLC6A7DPP4
	SCHEMBL21917399	0.80	TRPV1 (0.48)	TRPV1RIPK1GLSSLC6A7SLC6A2
	SCHEMBL2603222	0.79	PLD1 (0.53)	ACHEDPP4DPP8DPP9
	SCHEMBL2000100	0.78	HTR3E (0.54)	TRPV1RIPK1GLSSLC6A7DPP4
	SCHEMBL3715603	0.78	RIPK1 (0.48)	TRPV1RIPK1GLSSLC6A7DPP4
	SCHEMBL21843784	0.78	TRPV1 (0.46)	TRPV1RIPK1GLSSLC6A7SLC6A2
	SCHEMBL12776572	0.77	TRPV1 (0.45)	TRPV1RIPK1GLSSLC6A7DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.