Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12938613 | 0.87 | CYP4F2 (0.40) | ALDH1A1TDP1LMNA | |
| SCHEMBL8384168 | 0.86 | ALDH1A1 (0.50) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL12938777 | 0.85 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL12164790 | 0.85 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL15457622 | 0.85 | LMNA (0.46) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL12564043 | 0.83 | CHRM5 (0.44) | ALDH1A1TSHRL3MBTL1LMNARAD52 | |
| SCHEMBL847248 | 0.82 | ALDH1A1 (0.48) | ALDH1A1ATMTSHRL3MBTL1LMNA | |
| SCHEMBL862911 | 0.82 | ALDH1A1 (0.47) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL15704809 | 0.81 | ALDH1A1 (0.35) | ALDH1A1TSHRLMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL18679884 | 0.80 | NAAA (0.46) | ALDH1A1TSHRHCAR2NAAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170114182-A1 | BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2017-04-27 | — | — | US | disclosed |
| US-9284404-B2 | Antimicrobial polymers and methods of manufacture thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2016-03-15 | — | — | US | disclosed |
| US-8496946-B2 | Antimicrobial hydrogels, methods of preparation thereof, and articles therefrom | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-07-30 | — | — | US | disclosed |
| US-8361495-B2 | Antimicrobial polymers and methods of manufacture thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-01-29 | — | — | US | disclosed |
| US-20130011457-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-01-10 | — | — | US | disclosed |
| US-20120231060-A1 | ANTIMICROBIAL HYDROGELS, METHODS OF PREPARATION THEREOF, AND ARTICLES THEREFROM | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH | 2012-09-13 | — | — | US | disclosed |
| US-20110151566-A1 | BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-23 | — | — | US | disclosed |
| US-20110150977-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130011457-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | MLEC, NOD2, PAM | ALDH1A1 3648/4885ATM 4539/4885TSHR 4155/4885 |
| US-20170114182-A1 | BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO | DCLRE1A, ODC1, MRTO4 | ALDH1A1 555/4885ATM 4063/4885TSHR 4384/4885 |
| US-20110150977-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | MLEC, NOD2, PAM | ALDH1A1 3648/4885ATM 4539/4885TSHR 4155/4885 |
| US-20120231060-A1 | ANTIMICROBIAL HYDROGELS, METHODS OF PREPARATION THEREOF, AND ARTICLES THEREFROM | CLTB, ITGAM, PICALM | ALDH1A1 3662/4885ATM 3501/4885TSHR 3625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.