Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21631837 | 0.81 | HSD17B10 (0.50) | KDM4EHSD17B10MAPTALDH1A1HPGD | |
| SCHEMBL1217073 | 0.79 | ALOX15 (0.57) | KDM4EHSD17B10MAPTALDH1A1HPGD | |
| SCHEMBL5211157 | 0.78 | ENPP3 (0.62) | KDM4EHSD17B10MAPTALDH1A1HPGD | |
| SCHEMBL28474694 | 0.78 | ENPP3 (0.62) | KDM4EHSD17B10MAPTALDH1A1HPGD | |
| SCHEMBL13930787 | 0.77 | KDM4E (1.00) | KDM4EHSD17B10MAPTALDH1A1HPGD | |
| SCHEMBL1478175 | 0.74 | TAAR1 (0.61) | KDM4EHSD17B10MAPTALDH1A1HPGD | |
| SCHEMBL3261588 | 0.74 | CASP3 (1.00) | KDM4EHSD17B10MAPTALDH1A1HPGD | |
| SCHEMBL5000800 | 0.74 | CASP3 (0.51) | KDM4EHSD17B10MAPTALDH1A1HPGD | |
| SCHEMBL28478085 | 0.73 | HDAC1 (0.49) | ALDH1A1NPC1RAB9ALTA4HS1PR1 | |
| SCHEMBL2095342 | 0.73 | HSD17B1 (0.62) | HSD17B10MAPTALDH1A1HPGDLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180070591-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2018-03-15 | — | — | US | claimed |
| EP-2944636-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES USING COMPOUNDS WITH THREE RINGS, ONE OF THEM A PYRROLE | Monsanto Technology LLC (US) | 2015-11-18 | — | — | EP | claimed |
| US-20180070591-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2018-03-15 | — | — | US | disclosed |
| US-20180070591-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2018-03-15 | — | — | US | disclosed |
| US-20180070591-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2018-03-15 | — | — | US | disclosed |
| US-9820486-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2017-11-21 | — | — | US | disclosed |
| US-9820486-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2017-11-21 | — | — | US | disclosed |
| US-9820486-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2017-11-21 | — | — | US | disclosed |
| US-20160262396-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2016-09-15 | — | — | US | disclosed |
| US-20160262396-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2016-09-15 | — | — | US | disclosed |
| US-20160262396-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2016-09-15 | — | — | US | disclosed |
| US-8017555-B2 | Compositions and methods for controlling nematodes | DIVERGENCE, INC. (US) | 2011-09-13 | — | — | US | disclosed |
| US-20110028320-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. | 2011-02-03 | — | — | US | disclosed |
| US-20110028320-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. | 2011-02-03 | — | — | US | disclosed |
| US-20110028320-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. | 2011-02-03 | — | — | US | disclosed |
| US-20100210849-A1 | Compositions and Methods for Controlling Nematodes | DIVERGENCE, INC. (US) | 2010-08-19 | — | — | US | disclosed |
| US-20100210849-A1 | Compositions and Methods for Controlling Nematodes | DIVERGENCE, INC. (US) | 2010-08-19 | — | — | US | disclosed |
| US-20100210849-A1 | Compositions and Methods for Controlling Nematodes | DIVERGENCE, INC. (US) | 2010-08-19 | — | — | US | disclosed |
| WO-2010093650-A2 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. (US) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010093650-A2 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. (US) | 2010-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180070591-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | ATL3, NOP2, PTMS | KDM4E 1933/4885HSD17B10 2406/4885MAPT 2871/4885 |
| US-20160262396-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | ATL3, NOP2, PTMS | KDM4E 1933/4885HSD17B10 2406/4885MAPT 2871/4885 |
| US-20100210849-A1 | Compositions and Methods for Controlling Nematodes | ATL3, NOP2, PTMS | KDM4E 1933/4885HSD17B10 2406/4885MAPT 2871/4885 |
| US-20110028320-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | ATL3, NOP2, PTMS | KDM4E 1933/4885HSD17B10 2406/4885MAPT 2871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.