Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 7/20 | 0.55 |
| ▸ | THRA | P10827 | 5/20 | 0.55 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | USP2 | O75604 | 4/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39086 | 1.00 | SIRT5 (0.58) | SIRT5THRBTHRASLC7A5HSD17B10 | |
| SCHEMBL25180570 | 0.91 | SLC7A5 (0.58) | SIRT5THRBTHRASLC7A5HSD17B10 | |
| SCHEMBL13957567 | 0.91 | SLC7A5 (0.58) | SIRT5THRBTHRASLC7A5HSD17B10 | |
| SCHEMBL20683113 | 0.90 | SIRT5 (0.73) | SIRT5THRBTHRAHSD17B10USP2 | |
| SCHEMBL19004799 | 0.90 | SIRT5 (0.73) | SIRT5THRBTHRAHSD17B10USP2 | |
| SCHEMBL3523032 | 0.89 | SIRT5 (0.51) | SIRT5THRBTHRASLC7A5HSD17B10 | |
| SCHEMBL3523029 | 0.89 | SIRT5 (0.51) | SIRT5THRBTHRASLC7A5HSD17B10 | |
| SCHEMBL26378959 | 0.89 | SIRT5 (0.51) | SIRT5THRBTHRASLC7A5HSD17B10 | |
| SCHEMBL19113631 | 0.88 | THRB (0.65) | SIRT5THRBTHRASLC7A5HSD17B10 | |
| SCHEMBL6825058 | 0.88 | THRB (0.65) | SIRT5THRBTHRASLC7A5HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382646-A1 | ENGINEERED ENZYMES AND METHODS FOR THE SYNTHESIS OF DIVERSE TYROSINE ANALOGS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2025-12-18 | — | — | US | claimed |
| US-12421534-B2 | Engineered enzymes and method for the synthesis of diverse tyrosine analogs | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2025-09-23 | — | — | US | claimed |
| WO-2025044786-A1 | PEPTIDES, DERIVATIVES THEREOF, AND USE OF SAME | 南京医科大学 | 2025-03-06 | — | — | WO | claimed |
| CN-117384253-A | Peptide, derivative and application thereof | 南京医科大学 | 2024-01-12 | — | — | CN | claimed |
| US-20230313245-A1 | Engineered Enzymes and Method for the Synthesis of Diverse Tyrosine Analogs | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-10-05 | — | — | US | claimed |
| WO-2023182469-A1 | METHOD FOR PRODUCING METHYL PHENOL | 三菱ケミカル株式会社 | 2023-09-28 | — | — | WO | claimed |
| WO-2023086520-A2 | ENGINEERED ENZYMES AND METHOD FOR THE SYNTHESIS OF DIVERSE TYROSINE ANALOGS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-05-19 | — | — | WO | claimed |
| EP-2662079-A1 | Uses of formulations of thyroid hormone antagonists and nanoparticulate forms thereof to increase chemosensivity and radiosensitivity in tumor or cancer cells | Ordway Research Institute, Inc. (US) | 2013-11-13 | — | — | EP | claimed |
| US-20120315320-A1 | USES OF FORMULATIONS OF THYROID HORMONE ANALOGS AND NANOPARTICULATE FORMS THEREOF TO INCREASE CHEMOSENSIVITY AND RADIOSENSITIVITY IN TUMOR OR CANCER CELLS | NANOPHARMACEUTICALS LLC | 2012-12-13 | — | — | US | claimed |
| US-20260125722-A1 | METHOD FOR PRODUCING METHYL COMPOUND | MITSUBISHI CHEMICAL CORPORATION (JP) | 2026-05-07 | — | — | US | disclosed |
| EP-4692363-A1 | METHOD FOR PRODUCING METHYL COMPOUND | Mitsubishi Chemical Corporation (JP) | 2026-02-11 | — | — | EP | disclosed |
| EP-4692361-A1 | METHOD FOR PRODUCING METHYL COMPOUND | Mitsubishi Chemical Corporation (JP) | 2026-02-11 | — | — | EP | disclosed |
| US-20250382646-A1 | ENGINEERED ENZYMES AND METHODS FOR THE SYNTHESIS OF DIVERSE TYROSINE ANALOGS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2025-12-18 | — | — | US | disclosed |
| US-12421534-B2 | Engineered enzymes and method for the synthesis of diverse tyrosine analogs | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2025-09-23 | — | — | US | disclosed |
| CN-1938042-B | Use of aromatic cationic peptides for the manufacture of a medicament for the reduction of oxidative damage | CORNELL RES FOUNDATION INC | 2010-06-02 | — | — | CN | disclosed |
| CN-100536909-C | method for preventing mitochondrial permeability transition | CORNELL RES FOUNDATION INC CLI (US) | 2009-09-09 | — | — | CN | disclosed |
| CN-101440124-A | Methods for preventing mitochondrial permeability transition | CORNELL RES FOUNDATION INC (US) | 2009-05-27 | — | — | CN | disclosed |
| CN-101296704-A | Methods for reducing CD36 expression | CORNELL RES FOUNDATION INC (US) | 2008-10-29 | — | — | CN | disclosed |
| CN-1938042-A | Methods for mitigating oxidative damage | CORNELL RES FOUNDATION INC (US) | 2007-03-28 | — | — | CN | disclosed |
| CN-1787831-A | Method for preventing mitochondrial permeability transition | CORNELL RES FOUNDATION INC (US) | 2006-06-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125722-A1 | METHOD FOR PRODUCING METHYL COMPOUND | GNMT, MTR, BHMT | SIRT5 2584/4885THRB 2934/4885THRA 2691/4885 |
| US-20120315320-A1 | USES OF FORMULATIONS OF THYROID HORMONE ANALOGS AND NANOPARTICULATE FORMS THEREOF TO INCREASE CHEMOSENSIVITY AND RADIOSENSITIVITY IN TUMOR OR CANCER CELLS | TSHR, TPO, THRA | SIRT5 772/4885THRB 5/4885THRA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.