Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12883791 | 0.89 | EP300 (0.37) | KDM4EMAPTMAOBADORA2AKMT2A | |
| SCHEMBL8541156 | 0.82 | PTGDR2 (0.40) | KDM4EMAPTMAOBADORA2ACTRB1 | |
| SCHEMBL1224879 | 0.81 | EP300 (0.46) | KDM4EADORA2AKMT2AMEN1ALDH1A1 | |
| SCHEMBL2152951 | 0.79 | CTRB1 (0.44) | KDM4EMAPTMAOBADORA2ACTRB1 | |
| SCHEMBL7122663 | 0.76 | ALDH1A1 (0.35) | SMN1; SMN2NPSR1ALDH1A1RAB9AMAPK1 | |
| SCHEMBL12883810 | 0.76 | CTRB1 (0.37) | MAPTCTRB1P2RX4SMN1; SMN2CYP2C19 | |
| SCHEMBL5858112 | 0.75 | SMN1; SMN2 (0.43) | KDM4EMAPTMAOBADORA2ACTRB1 | |
| SCHEMBL1225948 | 0.74 | EP300 (0.41) | MAOBADORA2ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7064563 | 0.73 | EP300 (0.41) | KDM4EMAPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL12883783 | 0.72 | ALOX15 (0.35) | KDM4EMAPTSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462133-B1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2014-09-24 | — | — | EP | disclosed |
| EP-2462133-B1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2014-09-24 | — | — | EP | disclosed |
| US-8318758-B2 | 5-fluoro-2-oxopyrimidine-1(2H)-carboxylate derivatives | DOW AGROSCIENCES, LLC (US) | 2012-11-27 | — | — | US | disclosed |
| US-8318758-B2 | 5-fluoro-2-oxopyrimidine-1(2H)-carboxylate derivatives | DOW AGROSCIENCES, LLC (US) | 2012-11-27 | — | — | US | disclosed |
| US-8318758-B2 | 5-fluoro-2-oxopyrimidine-1(2H)-carboxylate derivatives | DOW AGROSCIENCES, LLC (US) | 2012-11-27 | — | — | US | disclosed |
| EP-2462133-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | Dow AgroSciences LLC (US) | 2012-06-13 | — | — | EP | disclosed |
| WO-2011017544-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | disclosed |
| WO-2011017544-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | disclosed |
| US-20110034491-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | ADAMA MAKHTESHIM LTD. (IL) | 2011-02-10 | — | — | US | disclosed |
| US-20110034491-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | ADAMA MAKHTESHIM LTD. (IL) | 2011-02-10 | — | — | US | disclosed |
| US-20110034491-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | ADAMA MAKHTESHIM LTD. (IL) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034491-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | DDT, PFAS, CASP2 | KDM4E 689/4885MAPT 3688/4885MAOB 1295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.