SCHEMBL122601

SCHEMBL122601

COc1ccc2[nH]cc(C[C@H](N)C(=O)O)c2c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2B P41595 4/20 0.70
HTR1A P08908 4/20 0.70
HTR2A P28223 3/20 0.70
HTR2C P28335 3/20 0.70
KMT2A Q03164 5/20 0.69
MEN1 O00255 3/20 0.69
HSP90AA1 P07900 1/20 0.69
HSP90AB1 P08238 1/20 0.69
LTA4H P09960 1/20 0.69
PLA2G2A P14555 1/20 0.69
KDM4E B2RXH2 4/20 0.68
BLM P54132 4/20 0.68
PMP22 Q01453 4/20 0.68
MAPT P10636 3/20 0.68
TSHR P16473 3/20 0.68
LMNA P02545 2/20 0.68
NFKB1 P19838 2/20 0.68
HTR7 P34969 2/20 0.68
NPSR1 Q6W5P4 2/20 0.68
ALDH1A1 P00352 2/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1421284 1.00 HTR2B (0.70) HTR2BHTR1AHTR2AHTR2CKMT2A
SCHEMBL18029115 1.00 HTR2B (0.70) HTR2BHTR1AHTR2AHTR2CKMT2A
SCHEMBL122600 1.00 HTR2B (0.70) HTR2BHTR1AHTR2AHTR2CKMT2A
SCHEMBL2330863 1.00 HTR2B (0.70) HTR2BHTR1AHTR2AHTR2CKMT2A
Ammonia Solution, Strong SCHEMBL28594768 0.99 HTR2B (0.68) HTR2BHTR1AHTR2AHTR2CKMT2A
SCHEMBL1460676 0.90 KMT2A (0.61) HTR2BHTR1AHTR2AHTR2CKMT2A
SCHEMBL18029114 0.90 KMT2A (0.61) HTR2BHTR1AHTR2AHTR2CKMT2A
SCHEMBL1460679 0.90 KMT2A (0.61) HTR2BHTR1AHTR2AHTR2CKMT2A
SCHEMBL31370348 0.90 KMT2A (0.61) HTR2BHTR1AHTR2AHTR2CKMT2A
SCHEMBL1607394 0.90 HTR2B (0.70) HTR2BHTR1AHTR2AHTR2CKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1754 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727655-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF Mariana Oncology Inc. (US) 2026-04-22 EP claimed
EP-4727654-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF Mariana Oncology Inc. (US) 2026-04-22 EP claimed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US claimed
EP-3746467-B1 MODIFIED LIPIDATED RELAXIN B CHAIN PEPTIDES AND THEIR THERAPEUTIC USE SANOFI SA (FR) 2025-10-08 EP claimed
US-12415834-B2 GhR-binding peptide and composition comprising same PEPTIDREAM INC. (JP) 2025-09-16 US claimed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 US claimed
US-20250049970-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC (US) 2025-02-13 US claimed
US-12203115-B2 Universal platform for genetic code expansion TRUSTEES OF BOSTON COLLEGE (US) 2025-01-21 US claimed
US-20250011368-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC (US) 2025-01-09 US claimed
WO-2024259115-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC. (US) 2024-12-19 WO claimed
EP-0820766-A2 New topical compositions containing very low doses of melatonin or derivatives thereof and their use in cosmetics L'OREAL (FR) 1998-01-28 EP claimed
EP-0736770-A2 An immunoreactive conjugate, method for its preparation, antibodies to said conjugate and a pharmaceutical composition and diagnostic device containing them ANDA BIOLOGICALS S.A. (FR) 1996-10-09 EP claimed
EP-0214254-B1 MELATONIN COMPOSITIONS AND USES THEREOF CELLENA (CELL ENGINEERING) A.G. (CH) 1992-06-17 EP claimed
US-4762781-A COUPLED TO AMINE OR GUANIDINE GROUPS OF HAPTENS VIA REACTION WITH DIALDEHYDE, IMMUNOLOGY CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1988-08-09 US claimed
US-4746674-A Melatonin compositions and uses thereof CELLENA (CELL ENGINEERING) AG (CH) 1988-05-24 US claimed
EP-0229131-A1 USE OF MELATONIN OR RELATED COMPOUNDS FOR THE TREATMENT OF PSORIASIS CELLENA (CELL ENGENEERING) A.G. (CH) 1987-07-22 EP claimed
WO-1987000432-A2 USE OF MELATONIN OR RELATED COMPOUNDS FOR THE TREATMENT OF PSORIASIS CELLENA (CELL ENGINEERING) A.G. (CH) 1987-01-29 WO claimed
EP-0149405-A2 Antibodies capable of specifically recognizing haptenic groups, their preparation and application, and antigens for the preparation of these antibodies Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1985-07-24 EP claimed
US-3963572-A Fermentative process for the production of L-tryptophan and its derivatives AB BOFORS (SW) 1976-06-15 US claimed
US-3930948-A ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES AJINOMOTO CO., INC. (JA) 1976-01-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351573-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM HTR2B 2179/4885HTR1A 3830/4885HTR2A 3159/4885
US-12415834-B2 GhR-binding peptide and composition comprising same GHRHR, GHSR, GIPR HTR2B 1337/4885HTR1A 1979/4885HTR2A 1926/4885
US-20250049970-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF DLK1, DBNL, PDLIM5 HTR2B 4864/4885HTR1A 4862/4885HTR2A 4848/4885
US-20250011368-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF DLK1, DBNL, PDCD1LG2 HTR2B 4862/4885HTR1A 4863/4885HTR2A 4847/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT HTR2B 346/4885HTR1A 801/4885HTR2A 799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.