Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 4/20 | 0.70 |
| ▸ | HTR1A | P08908 | 4/20 | 0.70 |
| ▸ | HTR2A | P28223 | 3/20 | 0.70 |
| ▸ | HTR2C | P28335 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.59 |
| ▸ | BLM | P54132 | 3/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.59 |
| ▸ | MPO | P05164 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18029115 | 0.90 | HTR2B (0.70) | HTR2BHTR1AHTR2AHTR2CKDM4E | |
| SCHEMBL122601 | 0.90 | HTR2B (0.70) | HTR2BHTR1AHTR2AHTR2CKDM4E | |
| SCHEMBL1421284 | 0.90 | HTR2B (0.70) | HTR2BHTR1AHTR2AHTR2CKDM4E | |
| SCHEMBL2330863 | 0.90 | HTR2B (0.70) | HTR2BHTR1AHTR2AHTR2CKDM4E | |
| SCHEMBL122600 | 0.90 | HTR2B (0.70) | HTR2BHTR1AHTR2AHTR2CKDM4E | |
| Ammonia Solution, Strong SCHEMBL28594768 | 0.89 | HTR2B (0.68) | HTR2BHTR1AHTR2AHTR2CKDM4E | |
| SCHEMBL6302625 | 0.89 | HTR2B (0.68) | HTR2BHTR1AHTR2AHTR2CKDM4E | |
| SCHEMBL1196470 | 0.89 | HTR2B (0.68) | HTR2BHTR1AHTR2AHTR2CKDM4E | |
| Hydrochloric Acid SCHEMBL28152940 | 0.88 | HTR2B (0.67) | HTR2BHTR1AHTR2AHTR2CKDM4E | |
| SCHEMBL28594764 | 0.88 | HTR2B (0.67) | HTR2BHTR1AHTR2AHTR2CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11737462-B2 | Methods for modulating plant response to environmentally-induced stress | HOWARD UNIVERSITY (US) | 2023-08-29 | — | — | US | disclosed |
| US-20180009750-A1 | 5-METHOXYTRYPTOPHAN AND ITS DERIVATIVES AND USES THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2018-01-11 | — | — | US | disclosed |
| US-20150119250-A1 | METHODS FOR MODULATING PLANT RESPONSE TO ENVIRONMENTALLY-INDUCED STRESS | GEORGETOWN UNIVERSITY | 2015-04-30 | — | — | US | disclosed |
| US-20110081385-A1 | Compositions and Methods for Sleep Regulation | LIFESCAPE BIOSCIENCES INC. (US) | 2011-04-07 | — | — | US | disclosed |
| US-7799817-B2 | Compositions and methods for sleep regulation | LIFESCAPE BIOSCIENCES INC (US) | 2010-09-21 | — | — | US | disclosed |
| EP-1715742-A4 | COMPOSITIONS AND METHODS FOR SLEEP REGULATION | LIFESCAPE BIOSCIENCES INC (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1715742-A1 | COMPOSITIONS AND METHODS FOR SLEEP REGULATION | Lifescape Bioscience Incorporated (US) | 2006-11-02 | — | — | EP | disclosed |
| US-20050272690-A1 | Compositions and methods for sleep regulation | LIFESCAPE BIOSCIENCES INC. | 2005-12-08 | — | — | US | disclosed |
| WO-2005082143-A1 | COMPOSITIONS AND METHODS FOR SLEEP REGULATION | LIFESCAPE BIOSCIENCES INCORPORATED (US) | 2005-09-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11737462-B2 | Methods for modulating plant response to environmentally-induced stress | RACK1, ROS1, HSF1 | HTR2B 4628/4885HTR1A 3190/4885HTR2A 3247/4885 |
| US-20150119250-A1 | METHODS FOR MODULATING PLANT RESPONSE TO ENVIRONMENTALLY-INDUCED STRESS | RACK1, ROS1, HSF1 | HTR2B 4628/4885HTR1A 3190/4885HTR2A 3247/4885 |
| US-20180009750-A1 | 5-METHOXYTRYPTOPHAN AND ITS DERIVATIVES AND USES THEREOF | TPH1, HTR5A, HTR1A | HTR2B 18/4885HTR1A 3/4885HTR2A 6/4885 |
| US-20110081385-A1 | Compositions and Methods for Sleep Regulation | PER2, CRY1, CRY2 | HTR2B 49/4885HTR1A 360/4885HTR2A 201/4885 |
| US-20050272690-A1 | Compositions and methods for sleep regulation | PER2, CRY1, CRY2 | HTR2B 49/4885HTR1A 360/4885HTR2A 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.