Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.36 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12047456 | 0.91 | LPAR1 (0.42) | LPAR1LPAR3LPAR2TSHRLPAR6 | |
| SCHEMBL12047464 | 0.88 | LPAR1 (0.45) | LPAR1LPAR3LPAR2USP2TSHR | |
| SCHEMBL12301807 | 0.88 | LPAR1 (0.45) | LPAR1LPAR3LPAR2USP2TSHR | |
| SCHEMBL12047460 | 0.88 | LPAR1 (0.45) | LPAR1LPAR3LPAR2USP2TSHR | |
| SCHEMBL10023016 | 0.86 | THRB (0.40) | — | |
| SCHEMBL11955576 | 0.86 | THRB (0.40) | — | |
| SCHEMBL14616851 | 0.85 | HSD17B10 (0.40) | LPAR1LPAR3LPAR2USP2HTT | |
| SCHEMBL14616847 | 0.84 | HSD17B10 (0.46) | LPAR1LPAR3LPAR2USP2HTT | |
| SCHEMBL12412476 | 0.84 | LPAR1 (0.55) | LPAR1LPAR3LPAR2USP2TSHR | |
| SCHEMBL16574874 | 0.83 | CYP3A4 (0.50) | LPAR1LPAR3LPAR2USP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150224205-A1 | POLYMERIC CONJUGATES OF C-1 INHIBITORS | ENZON PHARMACEUTICALS, INC. | 2015-08-13 | — | — | US | disclosed |
| US-20140315826-A1 | POLYMERIC CONJUGATES OF C-1 INHIBITORS | BELROSE PHARMA, INC. (US) | 2014-10-23 | — | — | US | disclosed |
| US-20140309175-A1 | POLYMERIC CONJUGATES OF C1-INHIBITORS | BELROSE PHARMA INC (US) | 2014-10-16 | — | — | US | disclosed |
| US-8741283-B2 | Adenosine deaminase anticancer therapy | SIGMA-TAU RARE DISEASES, S.A. (PT) | 2014-06-03 | — | — | US | disclosed |
| US-20140039158-A1 | POLYMERIC CONJUGATES AND METHODS OF PREPARING THE SAME | BELROSE PHARMA, INC. (US) | 2014-02-06 | — | — | US | disclosed |
| US-8367065-B2 | Targeted polymeric prodrugs containing multifunctional linkers | ENZON PHARMACEUTICALS, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-20120289571-A1 | POLYMERIC CONJUGATES OF AROMATIC AMINE CONTAINING COMPOUNDS INCLUDING RELEASABLE UREA LINKER | ENZON PHARMACEUTICALS, INC. (US) | 2012-11-15 | — | — | US | disclosed |
| US-8071741-B2 | Stable recombinant adenosine deaminase | DEFIANTE FARMACEUTICA, S.A. (PT) | 2011-12-06 | — | — | US | disclosed |
| US-20110230420-A1 | RELEASABLE CONJUGATES FOR NUCLEIC ACIDS DELIVERY SYSTEMS | ENZON PHARMACEUTICALS, INC. (US) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140039158-A1 | POLYMERIC CONJUGATES AND METHODS OF PREPARING THE SAME | PHYKPL, LNPEP, DNPEP | LPAR1 2994/4885LPAR3 3019/4885LPAR2 3005/4885 |
| US-20110230420-A1 | RELEASABLE CONJUGATES FOR NUCLEIC ACIDS DELIVERY SYSTEMS | PHAX, KPNA6, KPNA2 | LPAR1 1037/4885LPAR3 959/4885LPAR2 829/4885 |
| US-20120289571-A1 | POLYMERIC CONJUGATES OF AROMATIC AMINE CONTAINING COMPOUNDS INCLUDING RELEASABLE UREA LINKER | AURKA, DSTYK, TYR | LPAR1 3069/4885LPAR3 3345/4885LPAR2 3395/4885 |
| US-20150224205-A1 | POLYMERIC CONJUGATES OF C-1 INHIBITORS | C1S, SERPINC1, C1R | LPAR1 1483/4885LPAR3 2389/4885LPAR2 2850/4885 |
| US-20140315826-A1 | POLYMERIC CONJUGATES OF C-1 INHIBITORS | C9, SERPINC1, C1R | LPAR1 1354/4885LPAR3 1946/4885LPAR2 2811/4885 |
| US-20140309175-A1 | POLYMERIC CONJUGATES OF C1-INHIBITORS | SERPINC1, C1S, C1R | LPAR1 1998/4885LPAR3 2089/4885LPAR2 2629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.