Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1230313 | 0.85 | MAOA (0.43) | SCN5AMAP4K4NPC1RAB9ANLRP3 | |
| SCHEMBL1230233 | 0.83 | TLR2 (0.46) | MAP4K4NPC1RAB9ANLRP3PSEN1 | |
| SCHEMBL1259273 | 0.83 | SCN5A (0.40) | SCN5AMAP4K4NPC1RAB9ANLRP3 | |
| SCHEMBL245370 | 0.78 | ALDH1A1 (0.48) | NPC1RAB9AALDH1A1KDM4EDRD1 | |
| SCHEMBL19244899 | 0.76 | MAP4K4 (0.50) | MAP4K4NPC1RAB9ANLRP3PTGS1 | |
| SCHEMBL4549457 | 0.76 | NPC1 (0.67) | MAP4K4NPC1RAB9ANLRP3ALDH1A1 | |
| SCHEMBL4549455 | 0.76 | NPC1 (0.58) | MAP4K4NPC1RAB9ANLRP3PTGS2 | |
| SCHEMBL1230778 | 0.73 | NPC1 (0.43) | MAP4K4NPC1RAB9ANLRP3CYP1A2 | |
| SCHEMBL18099021 | 0.73 | MEN1 (0.31) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL17082477 | 0.73 | NPC1 (0.44) | MAP4K4NPC1RAB9ANLRP3PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732109-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2017-08-15 | — | — | US | disclosed |
| US-9732109-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2017-08-15 | — | — | US | disclosed |
| US-9732109-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2017-08-15 | — | — | US | disclosed |
| EP-2247603-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-09-28 | — | — | EP | disclosed |
| EP-2247603-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-09-28 | — | — | EP | disclosed |
| US-9179681-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-11-10 | — | — | US | disclosed |
| US-9179681-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-11-10 | — | — | US | disclosed |
| US-9179681-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-11-10 | — | — | US | disclosed |
| EP-2461687-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-09-16 | — | — | EP | disclosed |
| EP-2461687-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-09-16 | — | — | EP | disclosed |
| US-20120122805-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-05-17 | — | — | US | disclosed |
| US-8178658-B2 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178658-B2 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178658-B2 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| WO-2011017504-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | disclosed |
| EP-2247603-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009102736-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2009-08-20 | — | — | WO | disclosed |
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES LLC (US) | 2009-08-20 | — | — | US | disclosed |
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES LLC (US) | 2009-08-20 | — | — | US | disclosed |
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES LLC (US) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DDT, ACHE, NANP | SCN5A 1781/4885MAP4K4 4393/4885NPC1 1008/4885 |
| US-20120122805-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | SCN5A 1874/4885MAP4K4 4597/4885NPC1 4139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.