SCHEMBL12314028

SCHEMBL12314028

CCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 14/20 0.88
▸ PGR P06401 8/20 0.88
▸ CYP3A4 P08684 3/20 0.88
▸ HIF1A Q16665 2/20 0.88
▸ CYP2C9 P11712 2/20 0.88
▸ ABCC3 O15438 1/20 0.88
▸ ABCC4 O15439 1/20 0.88
▸ ABCB11 O95342 1/20 0.88
▸ IL5 P05113 1/20 0.88
▸ NR3C2 P08235 1/20 0.88
▸ AR P10275 1/20 0.88
▸ CHRM1 P11229 1/20 0.88
▸ MMP9 P14780 1/20 0.88
▸ NFKB1 P19838 1/20 0.88
▸ THPO P40225 1/20 0.88
▸ SMN1; SMN2 Q16637 1/20 0.88
▸ HSD17B10 Q99714 1/20 0.88
▸ LMNA P02545 1/20 0.88
▸ BLM P54132 1/20 0.88
▸ PMP22 Q01453 1/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24622229 1.00 NR3C1 (0.88) NR3C1PGRCYP3A4HIF1ACYP2C9
SCHEMBL13652071 1.00 NR3C1 (0.88) NR3C1PGRCYP3A4HIF1ACYP2C9
Budesonide SCHEMBL13695912 0.94 NR3C1 (1.00) NR3C1PGRCYP3A4HIF1ACYP2C9
Budesonide SCHEMBL12396756 0.94 NR3C1 (1.00) NR3C1PGRCYP3A4HIF1ACYP2C9
Budesonide SCHEMBL13928654 0.94 NR3C1 (1.00) NR3C1PGRCYP3A4HIF1ACYP2C9
Budesonide SCHEMBL14452945 0.94 NR3C1 (1.00) NR3C1PGRCYP3A4HIF1ACYP2C9
Budesonide SCHEMBL1130417 0.94 NR3C1 (1.00) NR3C1PGRCYP3A4HIF1ACYP2C9
Budesonide SCHEMBL13871728 0.94 NR3C1 (1.00) NR3C1PGRCYP3A4HIF1ACYP2C9
Budesonide SCHEMBL21570019 0.94 NR3C1 (1.00) NR3C1PGRCYP3A4HIF1ACYP2C9
Budesonide SCHEMBL8056801 0.94 NR3C1 (1.00) NR3C1PGRCYP3A4HIF1ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 465 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250144040-A1 COMPOSITE PARTICLE FORMULATIONS AND APPLICATIONS THEREOF UNIV NORTH CAROLINA CHAPEL HILL (US) 2025-05-08 — — US claimed
US-20240408186-A1 TREATMENT OF PRIMARY BILIARY CHOLANGITIS (PBC) WITH TOLERIZING NANOPARTICLES COUR PHARMACEUTICALS DEVELOPMENT COMPANY INC. 2024-12-12 — — US claimed
EP-4419149-A1 TREATMENT OF PRIMARY BILIARY CHOLANGITIS (PBC) WITH TOLERIZING NANOPARTICLES Cour Pharmaceuticals Development Company Inc. (US) 2024-08-28 — — EP claimed
US-20230398131-A1 PHARMACEUTICAL SPRAY COMPOSITION COMPRISING A VITAMIN D ANALOGUE AND CORTICOSTEROID LEO PHARMA AS (DK) 2023-12-14 — — US claimed
EP-3843705-B1 PREPARATION OF NANOSUSPENSION COMPRISING NANOCRYSTALS OF ACTIVE PHARMACEUTICAL INGREDIENTS WITH LITTLE OR NO STABILIZING AGENTS CENTRE NAT RECH SCIENT (FR) 2023-11-29 — — EP claimed
WO-2023219526-A1 MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT PROKIN MILAN (RS) 2023-11-16 — — WO claimed
US-11786574-B2 Treatment of rhinosinusitis with p-glycoprotein inhibitors MASSACHUSETTS EYE AND EAR INFIRMARY (US) 2023-10-17 — — US claimed
US-20230310597-A1 Combination Of The Application Of Antibodies For Immunostimulation Together With Glucocorticoids LINDHOFER, HORST (DE) 2023-10-05 — — US claimed
WO-2023141278-A2 COMPOSITE PARTICLE FORMULATIONS AND APPLICATIONS THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2023-07-27 — — WO claimed
WO-2023070104-A1 TREATMENT OF PRIMARY BILIARY CHOLANGITIS (PBC) WITH TOLERIZING NANOPARTICLES COUR PHARMACEUTICALS DEVELOPMENT COMPANY INC. (US) 2023-04-27 — — WO claimed
US-20230082167-A1 NOVEL TRICYCLIC COMPOUNDS ABBVIE INC (US) 2023-03-16 — — US claimed
EP-4447988-B1 COMPOSITIONS FOR TREATING AUTOIMMUNE ARTHRITIS DEVINTEC SAGL (CH) 2026-05-27 — — EP disclosed
EP-3937966-B1 COMPOSITIONS AND METHODS FOR PROTECTING TYPE 2 ALVEOLAR EPITHELIAL CELLS (AEC2) REIN THERAPEUTICS INC (US) 2026-05-06 — — EP disclosed
EP-4735023-A2 COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE Piton Therapeutics, Inc. (US) 2026-05-06 — — EP disclosed
US-12617858-B2 Anti-Müllerian hormone receptor 2 antibodies and methods of use THE CLEVELAND CLINIC FOUNDATION (US) 2026-05-05 — — US disclosed
US-20220048903-A1 Anthelminthic Heterocyclic Compounds BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2022-02-17 — — US disclosed
US-11247989-B2 Therapeutic compounds and uses thereof GENENTECH, INC. (US) 2022-02-15 — — US disclosed
US-20220024962-A1 SOLID FORMS OF (2S,3S,4S,5R,6S)-3,4,5-TRIHYDROXY-6-(((4AR,10AR)-7-HYDROXY-1-PROPYL-1,2,3,4,4A,5,10,10A-OCTAHYDROBENZO[G]QUINOLIN-6-YL)OXY)TETRAHYDRO-2H-PYRAN-2-CARBOXYLIC ACID H. LUNDBECK A/S (DK) 2022-01-27 — — US disclosed
US-20110223203-A1 NANOCLUSTER COMPOSITIONS AND METHODS UNIVERSITY OF KANSAS 2011-09-15 — — US disclosed
US-7432261-B2 Anti-inflammatory phosphonate compounds GILEAD SCIENCES, INC. (US) 2008-10-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230398131-A1 PHARMACEUTICAL SPRAY COMPOSITION COMPRISING A VITAMIN D ANALOGUE AND CORTICOSTEROID CYP24A1, CYP2R1, VDR NR3C1 34/4885PGR 395/4885CYP3A4 227/4885
US-20220024962-A1 SOLID FORMS OF (2S,3S,4S,5R,6S)-3,4,5-TRIHYDROXY-6-(((4AR,10AR)-7-HYDROXY-1-PROPYL-1,2,3,4,4A,5,10,10A-OCTAHYDROBENZO[G]QUINOLIN-6-YL)OXY)TETRAHYDRO-2H-PYRAN-2-CARBOXYLIC ACID PARK7, PAH, HTR3D NR3C1 1601/4885PGR 697/4885CYP3A4 49/4885
US-11247989-B2 Therapeutic compounds and uses thereof EP300, HDAC1, CREBBP NR3C1 90/4885PGR 2107/4885CYP3A4 4474/4885
US-20220048903-A1 Anthelminthic Heterocyclic Compounds SDHA, PAH, PIGS NR3C1 3930/4885PGR 1393/4885CYP3A4 130/4885
US-20230082167-A1 NOVEL TRICYCLIC COMPOUNDS CYP11B2, CYP11B1, ABCB1 NR3C1 429/4885PGR 419/4885CYP3A4 12/4885
US-20250144040-A1 COMPOSITE PARTICLE FORMULATIONS AND APPLICATIONS THEREOF ANAPC7, SARS1, CORO1C NR3C1 1700/4885PGR 932/4885CYP3A4 1054/4885
US-12617858-B2 Anti-Müllerian hormone receptor 2 antibodies and methods of use TGFBR2, TNFSF11, TNFRSF9 NR3C1 2233/4885PGR 48/4885CYP3A4 4574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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