Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598097 | 0.82 | MEN1 (0.54) | POLBLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10952765 | 0.82 | NPSR1 (0.53) | KDM4EGAAMAPTALDH1A1MAPK1 | |
| SCHEMBL13966687 | 0.80 | NPC1 (0.53) | POLBKDM4EGAAMAPTALDH1A1 | |
| SCHEMBL2403850 | 0.80 | MEN1 (0.62) | GAATSHRLMNAMAPTALDH1A1 | |
| SCHEMBL3447255 | 0.79 | LMNA (0.50) | POLBGAALMNASMN1; SMN2MEN1 | |
| SCHEMBL10951354 | 0.79 | TSHR (0.63) | POLBKDM4EGAATSHRMAPT | |
| SCHEMBL11273760 | 0.76 | KDM4E (0.65) | POLBKDM4EGAATSHRLMNA | |
| SCHEMBL2557605 | 0.74 | ALDH1A1 (0.72) | POLBKDM4ETSHRLMNAMAPT | |
| SCHEMBL6004364 | 0.73 | TP53 (0.68) | KDM4ELMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1916615 | 0.72 | POLB (0.56) | POLBKDM4EGAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110213156-A1 | 5-MEMBERED HETEROCYCLIC COMPOUND | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110213156-A1 | 5-MEMBERED HETEROCYCLIC COMPOUND | RXRA, RXRG, RXRB | POLB 3549/4885KDM4E 2854/4885GAA 3182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.