Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5918772 | 0.98 | LMNA (0.43) | LMNACA12CA1CA2CA3 | |
| Benzenesulfonamide SCHEMBL6989482 | 0.82 | CA2 (0.52) | LMNACA12CA1CA2CA3 | |
| Benzenesulfonamide SCHEMBL9273975 | 0.78 | BRD4 (0.46) | LMNACA12CA1CA2CA3 | |
| SCHEMBL20870956 | 0.74 | GAA (0.47) | LMNABRD4BRD2EPHX2NPC1 | |
| SCHEMBL24950250 | 0.74 | BRD4 (0.47) | BRD4BRD2EPHX2CYP2A6CHRNB2 | |
| SCHEMBL4930668 | 0.73 | CA12 (0.46) | LMNACA12CA1CA2CA3 | |
| SCHEMBL8103815 | 0.73 | CA12 (0.46) | LMNACA12CA1CA2CA3 | |
| SCHEMBL6585306 | 0.73 | KCNA3 (0.42) | BRD4BRD2CYP2A6CYP3A4TDO2 | |
| SCHEMBL4399692 | 0.73 | CHRNB2 (0.45) | MAOBESR1ESR2BRD4KDM4E | |
| SCHEMBL5985206 | 0.73 | MAPT (0.53) | LMNABRD4NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 601 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12492193-B2 | Pyrazole derivatives for the treatment of cystic fibrosis | FONDAZIONE INSTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-12-09 | — | — | US | claimed |
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | claimed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | claimed |
| EP-1430037-A4 | ZONISAMIDE INTERMEDIATE AND SYNTHESIS | TEVA PHARMA (IL) | 2004-11-17 | — | — | EP | claimed |
| US-20040138471-A1 | Novel sulfonation method for zonisamide intermediate in zonisamide synthesis and their novel crystal forms | MENDELOVICI MARIOARA (IL) | 2004-07-15 | — | — | US | claimed |
| EP-1430037-A1 | ZONISAMIDE INTERMEDIATE AND SYNTHESIS | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2004-06-23 | — | — | EP | claimed |
| WO-2003020708-A1 | ZONISAMIDE INTERMEDIATE AND SYNTHESIS | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-03-13 | — | — | WO | claimed |
| US-20260102395-A1 | INHIBITING HISTONE DEACETYLASE 6 | EIKONIZO THERAPEUTICS, INC. (US) | 2026-04-16 | — | — | US | disclosed |
| US-20260062393-A1 | Compounds | CTXT PTY LTD (AU) | 2026-03-05 | — | — | US | disclosed |
| CN-121537357-A | N-tridentate methyl benzoisoxazole salt and preparation method and application thereof | 中国医学科学院药用植物研究所 | 2026-02-17 | — | — | CN | disclosed |
| CN-121537357-A | N-tridentate methyl benzoisoxazole salt and preparation method and application thereof | 中国医学科学院药用植物研究所 | 2026-02-17 | — | — | CN | disclosed |
| US-12492193-B2 | Pyrazole derivatives for the treatment of cystic fibrosis | FONDAZIONE INSTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-12-09 | — | — | US | disclosed |
| US-12365655-B2 | Compounds | CTXT PTY LTD (AU) | 2025-07-22 | — | — | US | disclosed |
| US-6255515-B1 | COORDINATION POLYMERIZATION CATALYSTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-0985674-A1 | ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR $g(a)-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING $g(a)-OLEFIN POLYMERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-5750542-A | Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors | PFIZER (US) | 1998-05-12 | — | — | US | disclosed |
| US-5538984-A | Methods of using piperidyl-benzisoxazole and benisothiazole derivatives as cholinesterase inhibitors | PFIZER INC. (US) | 1996-07-23 | — | — | US | disclosed |
| EP-0646115-A1 | HETEROCYCLIC-CYCLIC AMINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5171891-A | Using sulfur containing oxy acids and their salts | ALLIED-SIGNAL INC. (US) | 1992-12-15 | — | — | US | disclosed |
| WO-1992017475-A1 | HETEROCYCLIC-CYCLIC AMINE DERIVATIVES | PFIZER INC. (US) | 1992-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138471-A1 | Novel sulfonation method for zonisamide intermediate in zonisamide synthesis and their novel crystal forms | CA3, ARSA, CBS | LMNA 2371/4885CA12 64/4885CA1 10/4885 |
| US-20260062393-A1 | Compounds | SCN2B, ABCB11, SCN1B | LMNA 3274/4885CA12 906/4885CA1 1778/4885 |
| US-20260102395-A1 | INHIBITING HISTONE DEACETYLASE 6 | HDAC6, HDAC1, HDAC8 | LMNA 1902/4885CA12 1670/4885CA1 345/4885 |
| US-12492193-B2 | Pyrazole derivatives for the treatment of cystic fibrosis | CFTR, ABCC5, ABCC1 | LMNA 4394/4885CA12 4745/4885CA1 4868/4885 |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | LMNA 3704/4885CA12 2695/4885CA1 3211/4885 |
| US-12365655-B2 | Compounds | SLC10A1, ABCB11, PCSK9 | LMNA 1392/4885CA12 365/4885CA1 881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.