Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12349788 | 0.81 | HPGD (0.35) | MGLLHPGDMTNR1AMTNR1BLMNA | |
| SCHEMBL12349861 | 0.78 | ADRB2 (0.39) | HPGDALDH1A1MTNR1AMTNR1BADRB2 | |
| SCHEMBL12349763 | 0.78 | PLAAT3 (0.42) | ALDH1A1MTNR1AMTNR1BADRB2LMNA | |
| SCHEMBL13616974 | 0.76 | PLAAT3 (0.40) | ALDH1A1MTNR1AMTNR1BADRB2POLB | |
| SCHEMBL13616987 | 0.75 | ALOX5 (0.42) | MTNR1AMTNR1BADRB2 | |
| SCHEMBL12349867 | 0.71 | MGLL (0.47) | MGLLALDH1A1LMNAPOLBHTT | |
| SCHEMBL24434329 | 0.71 | MGLL (0.40) | MGLLHPGDALDH1A1LMNAPOLB | |
| SCHEMBL12349829 | 0.70 | L3MBTL1 (0.44) | MGLLHPGDALDH1A1LMNAHTT | |
| SCHEMBL12349787 | 0.68 | PTGS1 (0.60) | ALDH1A1LMNAPOLBHTTKMT2A | |
| SCHEMBL12349801 | 0.68 | TAAR1 (0.40) | MGLLMTNR1AMTNR1BLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190467-A1 | Biological Polysiloxanes | VISION CRC LIMITED (AU) | 2011-08-04 | — | — | US | disclosed |