Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.39 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.39 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.39 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12349763 | 0.96 | PLAAT3 (0.42) | ALOX5MTNR1AMTNR1BADRB2DRD2 | |
| SCHEMBL12349861 | 0.95 | ADRB2 (0.39) | ALOX5TRPV1MTNR1AMTNR1BADRB2 | |
| SCHEMBL13616974 | 0.88 | PLAAT3 (0.40) | MTNR1AMTNR1BADRB2DRD2DRD1 | |
| SCHEMBL12349758 | 0.84 | PLAAT3 (0.47) | ALOX5MTNR1AMTNR1BPLAAT3PLAAT5 | |
| SCHEMBL12349745 | 0.81 | ALOX5 (0.56) | ALOX5TRPV1 | |
| SCHEMBL12349788 | 0.79 | HPGD (0.35) | MTNR1AMTNR1BPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL13911611 | 0.78 | LMNA (0.39) | ALOX5 | |
| SCHEMBL12349742 | 0.77 | ALOX5 (0.57) | ALOX5TRPV1 | |
| SCHEMBL12349801 | 0.76 | TAAR1 (0.40) | MTNR1AMTNR1B | |
| SCHEMBL12349785 | 0.75 | MGLL (0.36) | MTNR1AMTNR1BADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090276042-A1 | Biological Polysiloxanes | VISION CRC LIMITED (AU) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090276042-A1 | Biological Polysiloxanes | PBK, B2M, CD79B | ALOX5 899/4885TRPV1 3235/4885MTNR1A 1599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.