Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NAAA | Q02083 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RBP4 | P02753 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 3/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16306693 | 0.85 | RAB9A (0.49) | HPGDRAB9ADYRK1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28222855 | 0.84 | SCN9A (0.48) | HPGDRAB9ASCN9ADYRK1ASMN1; SMN2 | |
| SCHEMBL3642370 | 0.74 | DYRK1A (0.55) | RAB9ADYRK1ASMN1; SMN2MAOB | |
| SCHEMBL17275047 | 0.74 | RAB9A (0.58) | RAB9ANAAASCN9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12353792 | 0.74 | MAOA (0.52) | HPGDRAB9ADYRK1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12271749 | 0.74 | SMN1; SMN2 (0.47) | HPGDRAB9ANAAASCN9ASMN1; SMN2 | |
| SCHEMBL417526 | 0.73 | DYRK1A (0.54) | RAB9ADYRK1AGFERMAOB | |
| SCHEMBL6982986 | 0.73 | DYRK1A (0.61) | HPGDRAB9ADYRK1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL602139 | 0.73 | HRH4 (0.60) | TDO2HRH4 | |
| SCHEMBL17092665 | 0.72 | RBP4 (0.43) | HPGDDYRK1ASMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351749-A1 | CARBAMATE COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2011-08-03 | — | — | EP | disclosed |