Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12354084 | 0.85 | HPGD (0.52) | RAB9AHPGDDYRK1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28222855 | 0.81 | SCN9A (0.48) | RAB9AHPGDDYRK1ASMN1; SMN2RBP4 | |
| SCHEMBL14020936 | 0.76 | TUBB4A (0.64) | RAB9ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17109225 | 0.76 | SMN1; SMN2 (0.59) | RAB9AHPGDTUBB4ATUBBTUBA3C | |
| SCHEMBL4156994 | 0.74 | PPARA (0.57) | RAB9ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28919886 | 0.74 | DYRK1A (0.63) | RAB9ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12353792 | 0.74 | MAOA (0.52) | RAB9AHPGDDYRK1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22479064 | 0.73 | TUBB4A (0.54) | RAB9ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17092665 | 0.72 | RBP4 (0.43) | HPGDDYRK1ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL16306773 | 0.70 | MAOB (0.43) | RAB9AHPGDSMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014199933-A1 | BICYCLIC NITROGEN-CONTAINING AROMATIC HETEROCYCLIC AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2014-12-18 | — | — | WO | disclosed |