Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12366256 | 0.95 | POLB (0.38) | CNR1TP53MAPTMEN1KMT2A | |
| SCHEMBL12366233 | 0.94 | CNR1 (0.42) | CNR1TP53MAPTMEN1KMT2A | |
| SCHEMBL12366212 | 0.90 | CNR1 (0.44) | CNR1HPGDTSHRHSD17B10ITGB1 | |
| SCHEMBL12366295 | 0.90 | ITGB1 (0.39) | CNR1TP53MAPTHPGDTSHR | |
| SCHEMBL12366245 | 0.89 | CNR1 (0.43) | CNR1TP53MAPTMEN1KMT2A | |
| SCHEMBL12366286 | 0.89 | MAPT (0.45) | TP53MAPTPOLBALDH1A1KDM4E | |
| SCHEMBL12366418 | 0.89 | MAPT (0.42) | TP53MAPTPOLBHPGDHSD17B10 | |
| SCHEMBL12366396 | 0.88 | RXRA (0.41) | CNR1TP53MAPTPOLBHPGD | |
| SCHEMBL12366278 | 0.88 | MAPT (0.45) | TP53MAPTPOLBALDH1A1KDM4E | |
| SCHEMBL12366740 | 0.88 | PTGS2 (0.35) | CNR1TP53MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998986-B2 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | disclosed |