Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18523608 | 0.82 | NFKB1 (0.33) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL20963211 | 0.82 | GABRR1 (0.39) | ALDH1A1GABRR1GABBR2GABBR1 | |
| SCHEMBL24493657 | 0.79 | — | — | |
| SCHEMBL19245830 | 0.78 | ALDH1A1 (0.30) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL13010113 | 0.77 | ALDH1A1 (0.40) | ALDH1A1TSHRMAPK1ANPEPERAP2 | |
| SCHEMBL23005111 | 0.75 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL9989406 | 0.75 | TSHR (0.41) | ALDH1A1TSHRMAPK1ANPEPERAP2 | |
| SCHEMBL7391772 | 0.74 | TSHR (0.33) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL21126665 | 0.74 | — | — | |
| SCHEMBL5933640 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989600-B2 | Bioconjugation; drug screening | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. | 2011-08-02 | — | — | US | disclosed |
| US-20080241959-A1 | Macrolide Compounds Containing Biotin and Photo-Affinity Group for Macrolide Target Identification | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2008-10-02 | — | — | US | disclosed |
| US-20080096830-A1 | Anti-Inflammatory Macrolide Conjugates | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2008-04-24 | — | — | US | disclosed |
| US-7157433-B2 | Compounds, compositions as carriers for steroid/nonsteroid anti-inflammatory; antienoplastic and antiviral active molecules | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB (HR) | 2007-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080241959-A1 | Macrolide Compounds Containing Biotin and Photo-Affinity Group for Macrolide Target Identification | BTD, HLCS, MRPL12 | ALDH1A1 4489/4885TSHR 1578/4885MAPK1 3356/4885 |
| US-20080096830-A1 | Anti-Inflammatory Macrolide Conjugates | NLRP3, IL1B, MPO | ALDH1A1 602/4885TSHR 4179/4885MAPK1 2251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.