SCHEMBL12376766

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26312823	0.92	POLB (0.49)	ELANESTSTDP1POLBAPEX1
	SCHEMBL12376762	0.89	ELANE (0.42)	ELANESTSTDP1POLBAPEX1
	SCHEMBL18775854	0.86	STS (0.48)	ELANESTSTDP1POLBKMT2A
	SCHEMBL16018735	0.86	ELANE (0.47)	ELANESTSTDP1POLBAPEX1
	SCHEMBL26312810	0.85	SERPINE1 (0.47)	ELANETDP1KMT2ATSHRLMNA
	SCHEMBL7073769	0.83	ALDH1A1 (0.57)	ELANESTSTDP1POLBAPEX1
	SCHEMBL7763002	0.82	LMNA (0.60)	ELANESTSTDP1POLBAPEX1
	SCHEMBL26312929	0.81	ESR1 (0.39)	ELANESTSTDP1POLBAPEX1
	SCHEMBL16351932	0.81	ELANE (0.52)	ELANESTSTDP1POLBAPEX1
	SCHEMBL16340780	0.81	ELANE (0.52)	ELANESTSTDP1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.