Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12417592 | 0.87 | ALDH1A1 (0.86) | ALDH1A1MEN1KMT2AKDM4EHSD17B2 | |
| SCHEMBL4865137 | 0.84 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL10568457 | 0.82 | MEN1 (0.64) | ALDH1A1MEN1KMT2AKDM4EHSD17B2 | |
| SCHEMBL12378894 | 0.82 | MEN1 (0.68) | ALDH1A1MEN1KMT2AKDM4EHSD17B2 | |
| SCHEMBL2848397 | 0.80 | MEN1 (0.70) | ALDH1A1MEN1KMT2AKDM4EHSD17B2 | |
| SCHEMBL31314527 | 0.80 | MEN1 (0.70) | ALDH1A1MEN1KMT2AKDM4EHSD17B2 | |
| SCHEMBL7120174 | 0.78 | ALDH1A1 (0.81) | ALDH1A1MEN1KMT2AKDM4EHSD17B2 | |
| SCHEMBL25966580 | 0.78 | HSD17B2 (0.68) | ALDH1A1MEN1KMT2AKDM4EHSD17B2 | |
| SCHEMBL1528398 | 0.78 | KMT2A (0.67) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL11336062 | 0.78 | MEN1 (0.47) | ALDH1A1MEN1KMT2AKDM4ERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190514-A1 | PYRONE ANALOG COMPOSITIONS AND METHODS | LIMERICK BIOPHARMA, INC. (US) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190514-A1 | PYRONE ANALOG COMPOSITIONS AND METHODS | CYP11B2, CYP11B1, GLS2 | ALDH1A1 3621/4885MEN1 535/4885KMT2A 4673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.