Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28818080 | 0.97 | GNAI3 (0.39) | GNAI3GNAO1GNAI1MEN1KMT2A | |
| Ethane SCHEMBL4231792 | 0.97 | GNAI3 (0.39) | GNAI3GNAO1GNAI1MEN1KMT2A | |
| SCHEMBL3326166 | 0.97 | — | — | |
| Water SCHEMBL27995849 | 0.95 | GNAI3 (0.41) | GNAI3GNAO1GNAI1MEN1KMT2A | |
| SCHEMBL28503023 | 0.92 | — | — | |
| SCHEMBL8778709 | 0.86 | GNAI3 (0.45) | GNAI3GNAO1GNAI1MEN1KMT2A | |
| SCHEMBL20000752 | 0.86 | — | — | |
| SCHEMBL3108678 | 0.85 | GNAI3 (0.52) | GNAI3GNAO1GNAI1MEN1KMT2A | |
| SCHEMBL13450968 | 0.85 | GNAI3 (0.52) | GNAI3GNAO1GNAI1MEN1KMT2A | |
| SCHEMBL3113034 | 0.83 | GNAI3 (0.60) | GNAI3GNAO1GNAI1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874286-A | Compound for degrading BTK kinase, pharmaceutical composition and pharmaceutical application thereof | 四川海思科制药有限公司 | 2022-08-09 | — | — | CN | claimed |
| CN-103420898-A | Diaryl piperidine derivatives and applications thereof as multiple-target-point antidepressants | SHANGHAI INST PHARM INDUSTRY | 2013-12-04 | — | — | CN | claimed |
| US-8431609-B2 | Process for preparation of pyrazole derivatives | SHAH DARMESH MAHENDRABHAI (IN) | 2013-04-30 | — | — | US | claimed |
| US-8148402-B2 | Isoindolinone derivatives having inhibitory activity against T-type calcium channel and method for preparation thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-04-03 | — | — | US | claimed |
| US-20100190988-A1 | PROCESS FOR PREPARATION OF PYRAZOLE DERIVATIVES | SHAH DARMESH MAHENDRABHAI | 2010-07-29 | — | — | US | claimed |
| WO-2010005148-A2 | NOVEL ISOINDOLINONE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST T-TYPE CALCIUM CHANNEL AND METHOD FOR PREPARATION THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2010-01-14 | — | — | WO | claimed |
| US-20100004286-A1 | NOVEL ISOINDOLINONE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST T-TYPE CALCIUM CHANNEL AND METHOD FOR PREPARATION THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2010-01-07 | — | — | US | claimed |
| WO-2008102367-A1 | PROCESS FOR PREPARATION OF PYRAZOLE DERIVATIVES | SHAH DARMESH MAHENDRABHAI (IN) | 2008-08-28 | — | — | WO | claimed |
| US-20060292326-A1 | Optical data store comprising a cobalt phthalocyanine with an axial substituent and axial ligand in an information photoinscribtible layer | LANXESS DEUTSCHLAND GMBH (DE) | 2006-12-28 | — | — | US | claimed |
| EP-1563014-A1 | OPTICAL DATA MEMORIES COMPRISING COBALT PHTALOCYANIN WITH AN AXIAL SUBSTITUENT AND AXIAL LIGAND IN AN INFORMATION PHOTOINSCRIBTIBLE LAYER | LANXESS Deutschland GmbH (DE) | 2005-08-17 | — | — | EP | claimed |
| WO-2004046253-A1 | OPTICAL DATA MEMORIES COMPRISING COBALT PHTALOCYANIN WITH AN AXIAL SUBSTITUENT AND AXIAL LIGAND IN AN INFORMATION PHOTOINSCRIBTIBLE LAYER | LANXESS DEUTSCHLAND GMBH (DE) | 2004-06-03 | — | — | WO | claimed |
| US-6713146-B2 | SINGLY RECORDABLE COMPACT DISC (CD-R) | BAYER AKTIENGESELLSCHAFT (DE) | 2004-03-30 | — | — | US | claimed |
| US-20020127366-A1 | Optical data stores containing a Co-phthalocyanine complex in the information layer recordable using light | LANXESS DEUTSCHLAND GMBH (DE) | 2002-09-12 | — | — | US | claimed |
| EP-0064445-B1 | N-SUBSTITUTED 2,4-DIALKOXYBENZENE SULFON AMIDES | CHOAY S.A. (FR) | 1984-10-24 | — | — | EP | claimed |
| EP-0064445-A1 | N-substituted 2,4-dialkoxybenzene sulfon amides | CHOAY S.A. (FR) | 1982-11-10 | — | — | EP | claimed |
| JP-59027870-A | — | — | None | — | — | JP | disclosed |
| US-20230159508-A1 | INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2023-05-25 | — | — | US | disclosed |
| US-4113709-A | Polyquaternary polythiazines | PETROLITE CORPORATION (US) | 1978-09-12 | — | — | US | disclosed |
| US-4001224-A | 4-SUBSTITUTED-2, 3-DIHYDRO-1-BENZOXEPIN-3, 5-DIONES AND TAUTOMERS | WARNER-LAMBERT COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3991082-A | 4-Substituted-2,3-dihydro-1-benzoxepin-3,5-diones and tautomers | WARNER-LAMBERT COMPANY (US) | 1976-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190988-A1 | PROCESS FOR PREPARATION OF PYRAZOLE DERIVATIVES | PDXK, PYCR1, PPOX | GNAI3 1681/4885GNAO1 1947/4885GNAI1 2198/4885 |
| US-20230159508-A1 | INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE | RIPK1, RIPK2, RIPK4 | GNAI3 416/4885GNAO1 1921/4885GNAI1 294/4885 |
| US-20100004286-A1 | NOVEL ISOINDOLINONE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST T-TYPE CALCIUM CHANNEL AND METHOD FOR PREPARATION THEREOF | CACNA1I, CACNA1G, CACNA1E | GNAI3 948/4885GNAO1 1217/4885GNAI1 687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.