SCHEMBL12405342

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8903484	0.90	NQO2 (0.55)	NQO2CA2MTNR1ACDYLCYP1A2
	SCHEMBL8903462	0.88	NQO2 (0.52)	NQO2CA2MTNR1ACDYLKDM4E
	SCHEMBL1960375	0.84	KDM4E (0.46)	NQO2CA2MTNR1ACYP1A2CYP2D6
	SCHEMBL31618137	0.82	HTR6 (0.42)	NQO2MTNR1A
	SCHEMBL1880150	0.82	HTR2A (0.60)	NQO2MTNR1A
	SCHEMBL9740695	0.81	NQO2 (0.48)	NQO2CA2MTNR1ACDYLCYP1A2
	Ethylene Glycol SCHEMBL4591884	0.80	NQO2 (0.47)	NQO2CA2MTNR1ACDYLTDP1
	SCHEMBL5966612	0.79	NQO2 (0.47)	NQO2CA2MTNR1ACDYLKDM4E
	SCHEMBL29596281	0.79	NQO2 (0.47)	NQO2CA2MTNR1ACDYLKDM4E
	SCHEMBL548862	0.78	NQO2 (0.46)	NQO2CA2MTNR1ACDYLCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.