SCHEMBL12415889

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11964296	0.82	SLC6A2 (0.33)	CYP2D6SLC6A2SLC6A4HTTSLC6A3
	SCHEMBL2192132	0.82	CYP2D6 (0.35)	CYP2D6SLC6A2SLC6A4POLBSLC6A3
	SCHEMBL16858730	0.77	THRB (0.40)	CA1CA2THRBHTTPOLB
	SCHEMBL16974322	0.73	POLB (0.49)	CYP2D6SLC6A2SLC6A4POLBSLC6A3
	SCHEMBL9610355	0.72	SLC6A2 (0.34)	CYP2D6SLC6A2SLC6A4HTTSLC6A3
	SCHEMBL9610365	0.70	SLC6A2 (0.34)	CYP2D6SLC6A2SLC6A4POLBSLC6A3
	SCHEMBL19335269	0.70	SLC6A2 (0.41)	CYP2D6SLC6A2SLC6A4SLC6A3ALDH1A1
	SCHEMBL9610398	0.69	ALDH1A1 (0.33)	CYP2D6SLC6A2SLC6A4HTTPOLB
	SCHEMBL2194689	0.69	PIN1 (0.36)	POLBALDH1A1LMNAHPGDSMN1; SMN2
	SCHEMBL18355101	0.69	THRB (0.40)	CA1CA2THRBHTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.