Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 7/20 | 0.45 |
| ▸ | FNTB | P49356 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6345506 | 0.81 | ALDH1A1 (0.59) | TBXAS1KDM4EALDH1A1 | |
| SCHEMBL8253461 | 0.79 | CHRNB2 (0.56) | TBXAS1CHRNB2CHRNA7CHRNA4KDM4E | |
| SCHEMBL13654133 | 0.78 | HTR6 (0.52) | CHRNB2CHRNA7CHRNA4FNTAFNTB | |
| SCHEMBL7749049 | 0.77 | TBXAS1 (0.52) | TBXAS1CHRNB2CHRNA7CHRNA4KDM4E | |
| SCHEMBL10953031 | 0.77 | HTR6 (0.58) | FNTAFNTB | |
| SCHEMBL6341806 | 0.75 | TBXAS1 (0.54) | TBXAS1FNTAFNTB | |
| SCHEMBL13408067 | 0.75 | TBXAS1 (0.56) | TBXAS1CHRNB2CHRNA7CHRNA4KDM4E | |
| SCHEMBL11346119 | 0.72 | TBXAS1 (1.00) | TBXAS1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11488603 | 0.71 | TBXAS1 (0.97) | TBXAS1SMN1; SMN2 | |
| SCHEMBL6216616 | 0.71 | CHRNB2 (0.55) | TBXAS1CHRNB2CHRNA7CHRNA4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977370-B2 | (Hetero)aryl cyclohexane derivatives | GRUENENTHAL GMBH (DE) | 2011-07-12 | — | — | US | disclosed |
| US-20090247573-A1 | (HETERO)ARYL CYCLOHEXANE DERIVATIVES | GRUNENTHAL GMBH (DE) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247573-A1 | (HETERO)ARYL CYCLOHEXANE DERIVATIVES | OPRL1, OPRM1, OPRD1 | TBXAS1 918/4885CHRNB2 171/4885CHRNA7 221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.