SCHEMBL12445136

SCHEMBL12445136

O=C1CC(=O)c2cc3cc4c(cc3cc21)C(=O)OC4=O

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
TYMS P04818 2/20 0.38
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
ALOX5 P09917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10001437 0.90 ALOX15 (0.43) ALOX15TDP1TYMSALDH1A1KDM4E
SCHEMBL14453946 0.84 ALDH1A1 (0.36) ALOX15ALDH1A1KDM4EHPGD
SCHEMBL26189812 0.84 ALOX15 (0.39) ALOX15TDP1TYMSALDH1A1KDM4E
SCHEMBL26189813 0.77 MAOA (0.38) ALOX15TDP1ALDH1A1
SCHEMBL2600187 0.77 ALOX15 (0.43) ALOX15TDP1ALDH1A1KDM4EHPGD
SCHEMBL2604369 0.76 ALDH1A1 (0.46) ALOX15TDP1ALDH1A1KDM4EHPGD
SCHEMBL19481556 0.76 ALOX15 (0.36) ALOX15TDP1TYMSALDH1A1
SCHEMBL26189815 0.76 NPC1 (0.40) ALOX15TDP1ALDH1A1KDM4EHPGD
SCHEMBL182339 0.75 ALDH1A1 (0.48) ALOX15ALDH1A1KDM4EHPGD
SCHEMBL28945806 0.75 ALDH1A1 (0.48) ALOX15ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9771519-B2 Liquid crystal display device and method for manufacturing same JNC CORPORATION (JP) 2017-09-26 US disclosed
US-20170160594-A1 Polymer Used For Orientation Film Material and Method For Preparing Orientation Film SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2017-06-08 US disclosed
EP-2749589-A1 Hardener for epoxy resin systems and use thereof Evonik Industries AG (DE) 2014-07-02 EP disclosed
US-8753542-B2 Thermally stable conducting polymers, methods of making, and methods of use thereof THE UNIVERSITY OF CONNECTICUT (US) 2014-06-17 US disclosed
US-20140005344-A1 HARDENER FOR EPOXY RESIN SYSTEMS AND USE THEREOF EVONIK INDUSTRIES AG (DE) 2014-01-02 US disclosed
US-8323979-B2 Method for the determination of an analyte comprising a primary amino group, and kit for labeling said analyte BRAINS ONLINE HOLDING B.V. (NL) 2012-12-04 US disclosed
US-20110168951-A1 THERMALLY STABLE CONDUCTING POLYMERS, METHODS OF MAKING, AND METHODS OF USE THEREOF THE UNIVERSITY OF CONNECTICUT 2011-07-14 US disclosed
US-7914863-B2 Liquid crystal alignment solution DAXIN MATERIAL CORPORATION (TW) 2011-03-29 US disclosed
US-20100184231-A1 Method for the determination of an analyte comprising a primary amino group, and kit for labeling said analyte BRAINS ONLINE HOLDING B.V. (NL) 2010-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100184231-A1 Method for the determination of an analyte comprising a primary amino group, and kit for labeling said analyte AADAT, SRMS, DDC ALOX15 4097/4885TDP1 3098/4885TYMS 2158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.