SCHEMBL10001437

SCHEMBL10001437

O=C1CC(=O)c2cc3c(cc21)C(=O)OC3=O

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 2/20 0.38
TYMS P04818 1/20 0.36
MAPT P10636 1/20 0.31
RECQL P46063 1/20 0.31
KMT2A Q03164 1/20 0.31
MCL1 Q07820 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
BCHE P06276 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12445136 0.90 ALOX15 (0.40) ALOX15TDP1ALDH1A1TYMSKDM4E
SCHEMBL26189812 0.88 ALOX15 (0.39) ALOX15TDP1ALDH1A1TYMSKDM4E
SCHEMBL26189813 0.85 MAOA (0.38) ALOX15TDP1ALDH1A1BCHECES1
SCHEMBL19481556 0.84 ALOX15 (0.36) ALOX15TDP1ALDH1A1TYMS
SCHEMBL3993249 0.83 TDP1 (0.59) ALOX15TDP1ALDH1A1TYMSKMT2A
SCHEMBL14453945 0.83 ALDH1A1 (0.33) ALDH1A1MAPTRECQLKMT2AMCL1
SCHEMBL26189815 0.80 NPC1 (0.40) ALOX15TDP1ALDH1A1MAPTKMT2A
SCHEMBL12617282 0.77 MAOA (0.44) ALOX15TDP1ALDH1A1MAPTHPGD
SCHEMBL16543902 0.77 MAOA (0.44) ALOX15TDP1ALDH1A1MCL1
SCHEMBL15362268 0.77 KDM4E (0.33) ALOX15TDP1ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240024828-A1 HALOGEN-SUBSTITUTED 9,9-BIS(4-AMINOPHENYL)FLUORENE BASED POLYIMIDE MEMBRANES FOR GAS SEPARATION APPLICATIONS SAUDI ARABIAN OIL COMPANY (SA) 2024-01-25 US disclosed
US-11773288-B2 Modified polyamic acid, preparation method thereof, and preparation method of composite film WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-10-03 US disclosed
US-20230279183-A1 POLYIMIDE PRECURSOR COMPOSITION, POLYIMIDE FILM FORMED FROM THE SAME AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE USING THE SAME DONGWOO FINE-CHEM CO., LTD. (KR) 2023-09-07 US disclosed
US-11746083-B2 Compound, resin composition and laminated substrate thereof INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-09-05 US disclosed
US-20230192956-A1 FILM, MULTILAYER ELECTRONIC DEVICE, AND MANUFACTURING METHOD OF THE FILM SKC CO., LTD. (KR) 2023-06-22 US disclosed
US-11667757-B2 Polymer, composition, and polysiloxane-polyimide material thereof INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-06-06 US disclosed
US-11667759-B2 Polyimide composite, a method of preparing thereof, and application thereof WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-06-06 US disclosed
US-20230127585-A1 THERMOPLASTIC COMPOSITION AND METHOD OF PREPARING THE SAME TAIWAN TEXTILE RESEARCH INSTITUTE (TW) 2023-04-27 US disclosed
US-10457779-B2 Tetracarboxylic acid diester compound, polyimide precursor polymer and method for producing the same, negative photosensitive resin composition, positive photosensitive resin composition, patterning process, and method for forming cured film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-10-29 US disclosed
US-20180138509-A1 CATHODE ELECTRODE MATERIAL AND LITHIUM SULFUR BATTERY USING THE SAME TSINGHUA UNIVERSITY (CN) 2018-05-17 US disclosed
US-20120269970-A1 CLEANING METHOD AND FILM DEPOSITING METHOD TOKYO ELECTRON LIMITED (JP) 2012-10-25 US disclosed
US-20120160393-A1 METHOD FOR MAKING BISTABLE NEMATIC LIQUID-CRYSTAL DEVICES CDC PROPRIETE INTELLECTUELLE (FR) 2012-06-28 US disclosed
US-20110168951-A1 THERMALLY STABLE CONDUCTING POLYMERS, METHODS OF MAKING, AND METHODS OF USE THEREOF THE UNIVERSITY OF CONNECTICUT 2011-07-14 US disclosed
US-20100184231-A1 Method for the determination of an analyte comprising a primary amino group, and kit for labeling said analyte BRAINS ONLINE HOLDING B.V. (NL) 2010-07-22 US disclosed
US-20100125134-A1 METHOD OF SEPARATING GENOMIC DNA AND PLASMID DNA FROM EACH OTHER AND KIT THEREFOR SAMSUNG ELECTRONICS, CO., LTD. (KR) 2010-05-20 US disclosed
US-20090087748-A1 NEGATIVE ACTIVE MATERIAL FOR RECHARGEABLE LITHIUM BATTERY, AND NEGATIVE ELECTRODE FOR RECHARGEABLE LITHIUM BATTERY, AND RECHARGEABLE LITHIUM BATTERY INCLUDING SAME SAMSUNG SDI CO., LTD. (KR) 2009-04-02 US disclosed
US-20090011250-A1 Composite Insulated Conductor U.S.A. AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2009-01-08 US disclosed
US-20070265416-A1 POLYIMIDE BLEND WITH TAILORABLE PROPERTIES GENERAL ELECTRIC COMPANY (US) 2007-11-15 US disclosed
US-20070265417-A1 CROSSLINKED POLYIMIDE COPOLYMER MATERIAL GENERAL ELECTRIC COMPANY (US) 2007-11-15 US disclosed
US-20070265421-A1 METHOD FOR MAKING A PREPOLYMER POLYIMIDE RESIN BLEND GENERAL ELECTRIC COMPANY (US) 2007-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100125134-A1 METHOD OF SEPARATING GENOMIC DNA AND PLASMID DNA FROM EACH OTHER AND KIT THEREFOR KHSRP, SLC39A11, PCNA ALOX15 4279/4885TDP1 556/4885ALDH1A1 4394/4885
US-11746083-B2 Compound, resin composition and laminated substrate thereof ALOX12, ALOX15, ALOX5 ALOX15 2/4885TDP1 4148/4885ALDH1A1 169/4885
US-10457779-B2 Tetracarboxylic acid diester compound, polyimide precursor polymer and method for producing the same, negative photosensitive resin composition, positive photosensitive resin composition, patterning process, and method for forming cured film ARCN1, COL1A1, F12 ALOX15 989/4885TDP1 1071/4885ALDH1A1 1916/4885
US-20100184231-A1 Method for the determination of an analyte comprising a primary amino group, and kit for labeling said analyte AADAT, SRMS, DDC ALOX15 4097/4885TDP1 3098/4885ALDH1A1 58/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.