SCHEMBL1244972

SCHEMBL1244972

CC1(C)CCCC(C)(O)C1=O

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.35
POLB P06746 1/20 0.32
LMNA P02545 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL506194 0.81 ACHE (0.41) ACHEPOLB
SCHEMBL3129262 0.75 ACHE (0.37) ACHEPOLB
SCHEMBL11127724 0.70
SCHEMBL966903 0.69 ACHE (0.41) ACHEPOLB
SCHEMBL2692984 0.68 KDM4E (0.31) ACHE
SCHEMBL2458387 0.67 ACHE (0.40) ACHEPOLBLMNA
SCHEMBL7548140 0.67 ACHE (0.40) ACHEPOLB
SCHEMBL11819919 0.67
SCHEMBL18339311 0.66 CYP1A2 (0.38) LMNACYP2C9
SCHEMBL18339312 0.66 CYP1A2 (0.38) LMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592621-B2 Precursor compounds of sweet taste receptor antagonists for the prevention or treatment of disease SYMRISE AG (DE) 2013-11-26 US claimed
US-20110045069-A1 PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE SYMRISE GMBH CO. KG (DE) 2011-02-24 US claimed
EP-2007221-A1 CAROTENOID-CONTAINING DIETARY SUPPLEMENT Chemaphor Inc. (CA) 2008-12-31 EP claimed
WO-2007112587-A1 CAROTENOID-CONTAINING DIETARY SUPPLEMENT CHEMAPHOR INC. (CA) 2007-10-11 WO claimed
US-20260033524-A1 FLAVOR MODIFYING COMPOSITIONS CORN PRODUCTS DEV INC (US) 2026-02-05 US disclosed
EP-4561366-A1 FLAVOR MODIFYING COMPOSITION CORN Products Development Inc. (US) 2025-06-04 EP disclosed
US-20250081996-A1 FLAVOR MODIFYING COMPOSITION PURECIRCLE SDN BHD (MY) 2025-03-13 US disclosed
US-20240410055-A1 METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS MERCK PATENT GMBH (DE) 2024-12-12 US disclosed
CN-118961905-A Craniopharyngeoma serum metabolite spectrum, intestinal flora spectrum and application thereof 复旦大学附属华山医院 2024-11-15 CN disclosed
EP-4380375-A1 METHODS FOR THERMALLY INHIBITING STARCH CORN Products Development Inc. (US) 2024-06-12 EP disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
WO-2024026450-A1 FLAVOR MODIFYING COMPOSITION CORN PRODUCTS DEVELOPMENT, INC. (US) 2024-02-01 WO disclosed
EP-1306020-B1 Method of reduction of aroma extract and resulting extract KUBOYAMA KAZUKO (JP) 2005-06-08 EP disclosed
US-20040161769-A1 Comprises nucleotide sequences coding carotene-degrading oxidoreductase for use in detergents and preparation of food, cosmetics and perfume THE PROCTER & GAMBLE COMPANY 2004-08-19 US disclosed
WO-2004022683-A1 A MICROBIAL OXIDOREDUCTASE THE PROCTER & GAMBLE COMPANY (US) 2004-03-18 WO disclosed
EP-1398381-A1 A microbial oxidoreductase THE PROCTER & GAMBLE COMPANY (US) 2004-03-17 EP disclosed
EP-1306020-A1 Method of reduction of aroma extract and resulting extract Kuboyama, Kazuko (JP) 2003-05-02 EP disclosed
EP-0399619-B1 Process for preparing flavourings and perfumes based on one or more carotenoids as starting materials QUEST INT (NL) 1994-12-21 EP disclosed
US-5084292-A Autooxidizing carotenoids to form flavors or perfumes UNILEVER PATENT HOLDINGS B.V. (NL) 1992-01-28 US disclosed
EP-0399619-A1 Process for preparing flavourings and perfumes based on one or more carotenoids as starting materials QUEST INTERNATIONAL B.V. (NL) 1990-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 ACHE 505/4885POLB 4295/4885LMNA 4834/4885
US-20260033524-A1 FLAVOR MODIFYING COMPOSITIONS TAS2R42, TAS2R7, TAS2R31 ACHE 1327/4885POLB 4255/4885LMNA 1687/4885
US-20040161769-A1 Comprises nucleotide sequences coding carotene-degrading oxidoreductase for use in detergents and preparation of food, cosmetics and perfume CUTA, POLA1, POLL ACHE 397/4885POLB 5/4885LMNA 67/4885
US-20110045069-A1 PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE TAS1R2, TAS2R5, TAS2R1 ACHE 1688/4885POLB 3064/4885LMNA 3996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.