SCHEMBL1245102

SCHEMBL1245102

CC1OC(c2ccccc2)OC1C

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.48
CYP2C19 P33261 2/20 0.48
KMT2A Q03164 2/20 0.48
TSHR P16473 1/20 0.39
SLC6A2 P23975 1/20 0.36
ADRA1A P35348 1/20 0.36
HTR2B P41595 1/20 0.36
SLC6A3 Q01959 1/20 0.36
EPHX1 P07099 4/20 0.35
HTR1A P08908 1/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
CYP2D6 P10635 1/20 0.34
CHRNA7 P36544 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3092739 1.00 MEN1 (0.48) MEN1CYP2C19KMT2ATSHRSLC6A2
SCHEMBL877724 1.00 MEN1 (0.48) MEN1CYP2C19KMT2ATSHRSLC6A2
SCHEMBL3092749 1.00 MEN1 (0.48) MEN1CYP2C19KMT2ATSHRSLC6A2
SCHEMBL15436881 1.00 MEN1 (0.48) MEN1CYP2C19KMT2ATSHRSLC6A2
SCHEMBL15436882 1.00 MEN1 (0.48) MEN1CYP2C19KMT2ATSHRSLC6A2
SCHEMBL13356510 0.84 MEN1 (0.48) MEN1CYP2C19KMT2ATSHRSLC6A2
SCHEMBL3090030 0.78 CYP2C19 (0.48) MEN1CYP2C19KMT2ATSHRSLC6A2
SCHEMBL11892313 0.78 CYP2C19 (0.48) MEN1CYP2C19KMT2ATSHRSLC6A2
SCHEMBL12228274 0.78 CYP2C19 (0.48) MEN1CYP2C19KMT2ATSHRSLC6A2
SCHEMBL10484173 0.78 KCNA4 (0.41) MEN1CYP2C19KMT2AEPHX1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11780787-B2 Method for conversion of diols to olefin products UT-BATTELLE, LLC (US) 2023-10-10 US disclosed
US-20230242464-A1 METHOD FOR CONVERSION OF DIOLS TO OLEFIN PRODUCTS UT BATTELLE LLC (US) 2023-08-03 US disclosed
WO-2022007838-A1 METHOD FOR PREPARING GLUCOPYRANOSYL DERIVATIVES AND INTERMEDIATES THEREOF DONGGUAN HEC NEW DRUG R & D CO., LTD. (CN) 2022-01-13 WO disclosed
WO-2020143653-A1 PREPARATION METHOD FOR GLUCOPYRANOSYL DERIVATIVE AND INTERMEDIATE THEREOF 广东东阳光药业有限公司 2020-07-16 WO disclosed
EP-2292224-B1 Derivatives of lactiosole for preventing or treating diabetes SYMRISE AG (DE) 2018-03-07 EP disclosed
US-8592621-B2 Precursor compounds of sweet taste receptor antagonists for the prevention or treatment of disease SYMRISE AG (DE) 2013-11-26 US disclosed
US-8105978-B2 Thermal transfer ink sheet, ink cartridge, coating composition for dye layer of thermal transfer ink sheet, and thermal transfer recording method FUJIFILM CORPORATION (JP) 2012-01-31 US disclosed
EP-2292224-A1 Precursor compounds of sweet receptor antagonists for preventing or treating diabetes Symrise AG (DE) 2011-03-09 EP disclosed
US-20110045069-A1 PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE SYMRISE GMBH CO. KG (DE) 2011-02-24 US disclosed
US-20100248390-A1 COMPOSITIONS AND METHODS FOR IDENTIFYING LIGANDS OF ODORANT RECEPTORS DUKE UNIVERSITY (US) 2010-09-30 US disclosed
US-20080241434-A1 THERMAL TRANSFER INK SHEET, INK CARTRIDGE, COATING COMPOSITION FOR DYE LAYER OF THERMAL TRANSFER INK SHEET, AND THERMAL TRANSFER RECORDING METHOD FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242464-A1 METHOD FOR CONVERSION OF DIOLS TO OLEFIN PRODUCTS DUOX1, HMOX1, HAO2 MEN1 1294/4885CYP2C19 603/4885KMT2A 2775/4885
US-20110045069-A1 PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE TAS1R2, TAS2R5, TAS2R1 MEN1 1488/4885CYP2C19 3693/4885KMT2A 2910/4885
US-11780787-B2 Method for conversion of diols to olefin products DUOX1, HMOX1, HAO2 MEN1 1294/4885CYP2C19 603/4885KMT2A 2775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.