Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | ICMT | O60725 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 5/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | BLVRB | P30043 | 1/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31019133 | 0.83 | XDH (0.53) | XDHSLC22A12ABCC4ABCB11PGR | |
| SCHEMBL2344031 | 0.83 | XDH (0.53) | XDHSLC22A12ABCC4ABCB11PGR | |
| SCHEMBL17309854 | 0.82 | SLC6A9 (0.47) | ICMTALDH1A1GAAXDHSLC22A12 | |
| SCHEMBL27750629 | 0.82 | ALDH1A1 (0.42) | ALDH1A1GAAXDHSLC22A12SLC6A9 | |
| SCHEMBL2636175 | 0.82 | ALDH1A1 (0.42) | ALDH1A1GAAXDHSLC22A12AR | |
| SCHEMBL3746804 | 0.82 | AR (0.50) | MRGPRX4ICMTALDH1A1GAAXDH | |
| SCHEMBL437358 | 0.81 | TRPV4 (0.54) | MRGPRX4ALDH1A1GAASSTR4AR | |
| SCHEMBL28291444 | 0.80 | ALDH1A1 (0.45) | ALDH1A1GAAXDHSLC22A12SLC6A9 | |
| SCHEMBL25196562 | 0.79 | MRGPRX4 (0.50) | MRGPRX4ICMTALDH1A1SSTR4AR | |
| SCHEMBL19851607 | 0.79 | TRPV4 (0.45) | ALDH1A1GAASLC6A9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574952-B | Synthetic method of febuxostat intermediate | 安徽省庆云医药股份有限公司 | 2022-04-01 | — | — | CN | claimed |
| CN-109574952-A | A kind of synthetic method of febuxostat intermediate | 安徽省庆云医药股份有限公司 | 2019-04-05 | — | — | CN | claimed |
| CN-109574952-B | Synthetic method of febuxostat intermediate | 安徽省庆云医药股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-109574952-B | Synthetic method of febuxostat intermediate | 安徽省庆云医药股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-109574952-A | A kind of synthetic method of febuxostat intermediate | 安徽省庆云医药股份有限公司 | 2019-04-05 | — | — | CN | disclosed |
| WO-2011101867-A2 | SUBSTANTIALLY PURE SALTS OF FEBUXOSTAT AND PROCESSES FOR PREPARATION THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2011-08-25 | — | — | WO | disclosed |