Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 4/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | FOS | P01100 | 1/20 | 0.37 |
| ▸ | JUN | P05412 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2344031 | 0.83 | XDH (0.53) | XDHSLC22A12 | |
| SCHEMBL31019133 | 0.83 | XDH (0.53) | XDHSLC22A12 | |
| SCHEMBL3746804 | 0.81 | AR (0.50) | ALDH1A1GAASLC6A4KCNH2SLC6A3 | |
| SCHEMBL12455378 | 0.80 | MRGPRX4 (0.48) | ALDH1A1GAAKCNH2XDHSLC22A12 | |
| SCHEMBL17224522 | 0.79 | SLC6A4 (0.52) | ALDH1A1MAPTGAASLC6A4KCNH2 | |
| SCHEMBL27750629 | 0.78 | ALDH1A1 (0.42) | ALDH1A1GAAKCNH2XDHSLC22A12 | |
| SCHEMBL2636175 | 0.78 | ALDH1A1 (0.42) | ALDH1A1GAAKCNH2XDHSLC22A12 | |
| SCHEMBL17309854 | 0.78 | SLC6A9 (0.47) | ALDH1A1GAAKCNH2XDHSLC22A12 | |
| SCHEMBL4723254 | 0.78 | KDM1A (0.52) | ALDH1A1MAPTTHRBGPR55GAA | |
| SCHEMBL19851607 | 0.75 | TRPV4 (0.45) | ALDH1A1GAAKCNH2TRPV4SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574951-A | A kind of preparation method of Febuxostat | 安徽省庆云医药股份有限公司 | 2019-04-05 | — | — | CN | claimed |
| CN-109574951-A | A kind of preparation method of Febuxostat | 安徽省庆云医药股份有限公司 | 2019-04-05 | — | — | CN | disclosed |
| CN-109574951-A | A kind of preparation method of Febuxostat | 安徽省庆云医药股份有限公司 | 2019-04-05 | — | — | CN | disclosed |