SCHEMBL124733

SCHEMBL124733

COCCOCc1nc(C(F)(F)F)ccc1C(=O)C1=C(O)C2CCC(C2)C1=O

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.31
DRD4 P21917 2/20 0.31
HTR1A P08908 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
DRD3 P35462 1/20 0.31
HTR2B P41595 1/20 0.31
IDH1 O75874 1/20 0.31
RORC P51449 1/20 0.31
TUBB4A P04350 1/20 0.31
TUBB P07437 1/20 0.31
TUBA3C P0DPH7 1/20 0.31
TUBA1B P68363 1/20 0.31
TUBA4A P68366 1/20 0.31
TUBB4B P68371 1/20 0.31
TUBB3 Q13509 1/20 0.31
TUBB2A Q13885 1/20 0.31
TUBB8 Q3ZCM7 1/20 0.31
TUBA3E Q6PEY2 1/20 0.31
TUBA1A Q71U36 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14654290 1.00 DRD2 (0.31) DRD2DRD4HTR1AHTR2AHTR2C
SCHEMBL14242410 1.00 DRD2 (0.31) DRD2DRD4HTR1AHTR2AHTR2C
SCHEMBL124732 1.00 DRD2 (0.31) DRD2DRD4HTR1AHTR2AHTR2C
SCHEMBL31482986 1.00 DRD2 (0.31) DRD2DRD4HTR1AHTR2AHTR2C
SCHEMBL14180527 0.99 LIPC (0.31) DRD2DRD4HTR1AHTR2AHTR2C
SCHEMBL6466314 0.99 LIPC (0.31) DRD2DRD4HTR1AHTR2AHTR2C
Acetamide SCHEMBL337717 0.96 LIPC (0.30) LIPCLIPG
SCHEMBL12362081 0.94 TUBB4A (0.31) DRD2DRD4HTR1AHTR2AHTR2C
SCHEMBL13383645 0.93
SCHEMBL13255769 0.93 LIPG (0.30) LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022251154-A1 METHODS FOR WEED CONTROL IN LAWN OR TURF BAYER CROPSCIENCE LP (US) 2022-12-01 WO claimed
US-20220361498-A1 HERBICIDAL COMPOSITION SYNGENTA CROP PROTECTION LLC (US) 2022-11-17 US claimed
US-11395490-B2 Herbicidal composition SYNGENTA CROP PROTECTION, LLC (US) 2022-07-26 US claimed
US-10619138-B2 Herbicide-resistant hydroxyphenylpyruvate dioxygenases BASF SE (DE) 2020-04-14 US claimed
US-RE47666-E1 Herbicidal compositions BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-10-29 US claimed
EP-2427062-B1 A METHOD FOR INCREASING THE CROP YIELD OF AGRICULTURAL PLANTS UNDER ESSENTIALLY NON-EXISTENT PATHOGEN PRESSURE BAYER CROPSCIENCE LP (US) 2019-01-16 EP claimed
US-20160227788-A1 Method for Increasing the Vigor and/or Crop Yield of Agricultural Plants Under Essentially Non-Existent Pathogen Pressure BAYER CROPSCIENCE LP 2016-08-11 US claimed
US-RE46095-E1 Herbicidal compositions BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-08-09 US claimed
EP-2387569-B1 HERBCIDES SYNGENTA LTD (GB) 2016-06-15 EP claimed
EP-2375898-B1 NOVEL HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2015-09-16 EP claimed
US-20080254985-A1 Herbicidal Compositions Based on 3-Phenyluracils and N-[[4-[Cyclopropylamino)-Carbonyl]Phenyl]Sulfonyl]-2-Methoxybenzamide BASF SE (DE) 2008-10-16 US claimed
EP-1965648-A2 A METHOD FOR CONTROLLING AQUATIC WEEDS BASF SE (DE) 2008-09-10 EP claimed
EP-1605758-B1 HERBICIDAL MIXTURES BASED ON 3-PHENYLURACILS BASF SE (DE) 2008-09-10 EP claimed
EP-1937069-A2 HERBICIDAL COMPOSITIONS BASED ON 3-PHENYLURACILS AND N-[[4-[(CYCLOPROPYLAMINO)-CARBONYL]PHENYL]SULFONYL]-2-METHOXYBENZAMIDE BASF SE (DE) 2008-07-02 EP claimed
WO-2008071714-A1 MIXTURES COMPRISING 1-METHYLCYCLOPROPENE ROHM AND HAAS COMPANY (US) 2008-06-19 WO claimed
EP-1858328-A2 HERBICIDAL COMPOSITION Syngenta Participations AG (CH) 2007-11-28 EP claimed
WO-2007071761-A2 A METHOD FOR CONTROLLING AQUATIC WEEDS BASF SE (DE) 2007-06-28 WO claimed
WO-2007042447-A2 HERBICIDAL COMPOSITIONS BASED ON 3-PHENYLURACILS AND N-[[4-[(CYCLOPROPYLAMINO)-CARBONYL]PHENYL]SULFONYL]-2-METHOXYBENZAMIDE BASF SE (DE) 2007-04-19 WO claimed
US-20060293187-A1 Herbicidal mixtures based on 3-phenyluracils BASF AKTIENGESELLSCHAFT (DE) 2006-12-28 US claimed
WO-2006097322-A2 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2006-09-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060293187-A1 Herbicidal mixtures based on 3-phenyluracils CBR3, CYP2W1, DDT DRD2 413/4885DRD4 346/4885HTR1A 1384/4885
US-10619138-B2 Herbicide-resistant hydroxyphenylpyruvate dioxygenases HPD, PHPT1, DERA DRD2 2755/4885DRD4 1676/4885HTR1A 3946/4885
US-11395490-B2 Herbicidal composition TOP2B, GRM3, ATL3 DRD2 285/4885DRD4 243/4885HTR1A 179/4885
US-20080254985-A1 Herbicidal Compositions Based on 3-Phenyluracils and N-[[4-[Cyclopropylamino)-Carbonyl]Phenyl]Sulfonyl]-2-Methoxybenzamide DDT, ABCC5, CBR3 DRD2 837/4885DRD4 655/4885HTR1A 1133/4885
US-20220361498-A1 HERBICIDAL COMPOSITION DDT, TOP2B, TUBB3 DRD2 291/4885DRD4 244/4885HTR1A 303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.