Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167786 | 0.86 | TDP1 (0.37) | GAAHTR7TDP1HSD17B10CYP1A2 | |
| SCHEMBL13698347 | 0.83 | GAA (0.39) | GAAHTR7TDP1HSD17B10CYP1A2 | |
| SCHEMBL12648796 | 0.83 | ALDH1A1 (0.45) | GAAHTR7TDP1HSD17B10CYP1A2 | |
| SCHEMBL14421179 | 0.83 | CYP2C9 (0.35) | GAAHTR7TDP1HSD17B10CYP1A2 | |
| SCHEMBL9581649 | 0.81 | ALOX5 (0.38) | GAAHTR7TDP1HSD17B10CYP1A2 | |
| SCHEMBL1193860 | 0.81 | GAA (0.48) | GAAHSD17B10ALOX5MEN1KMT2A | |
| SCHEMBL13698343 | 0.80 | HTR6 (0.52) | HTR7HSD17B10HTR1DHTR6HTR2A | |
| SCHEMBL19193144 | 0.76 | HTR7 (0.53) | GAAHTR7TDP1HSD17B10CYP1A2 | |
| SCHEMBL9209940 | 0.69 | MEN1 (0.54) | GAAHTR7TDP1HSD17B10CYP1A2 | |
| SCHEMBL26989650 | 0.69 | HTR6 (0.68) | GAAHTR7TDP1HSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977359-B2 | 5-lipdxygenase-activating protein (FLAP) inhibitors | AMIRA PHARMACEUTICALS, INC. (US) | 2011-07-12 | — | — | US | disclosed |
| US-20090192171-A1 | 5-Lipoxygenase-Activating Protein (FLAP) Inhibitors | AMIRA PHARMACEUTICALS, INC. (US) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192171-A1 | 5-Lipoxygenase-Activating Protein (FLAP) Inhibitors | ALOX5, ALOX15B, ALOX15 | GAA 2900/4885HTR7 1680/4885TDP1 1428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.