Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.52 |
| ▸ | SIRT5 | Q9NXA8 | 5/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12514741 | 1.00 | KLK7 (0.54) | KLK7KLK5MAPTSIRT2SIRT1 | |
| SCHEMBL19945237 | 0.99 | KLK7 (0.54) | KLK7KLK5MAPTSIRT2SIRT1 | |
| SCHEMBL12515379 | 0.97 | KLK7 (0.52) | KLK7KLK5MAPTSIRT2SIRT1 | |
| SCHEMBL12514745 | 0.94 | KLK7 (0.55) | KLK7KLK5MAPTSIRT2SIRT1 | |
| SCHEMBL19219892 | 0.94 | KLK7 (0.54) | KLK7KLK5MAPTSIRT2SIRT1 | |
| SCHEMBL12779163 | 0.93 | KLK7 (0.54) | KLK7KLK5MAPTSIRT2SIRT1 | |
| SCHEMBL12518233 | 0.92 | KLK7 (0.52) | KLK7KLK5MAPTSIRT2SIRT1 | |
| SCHEMBL21371590 | 0.91 | KLK7 (0.52) | KLK7KLK5MAPTSIRT2SIRT1 | |
| SCHEMBL12778929 | 0.90 | SIRT2 (0.55) | SIRT2SIRT1SIRT5SIRT3 | |
| SCHEMBL12780067 | 0.90 | KLK7 (0.51) | KLK7KLK5MAPTSIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10603294-B2 | Compounds for use in treatment of mucositis | INNOVATION PHARMACEUTICALS INC. (US) | 2020-03-31 | — | — | US | disclosed |
| US-20190282521-A1 | Compounds For Use In Treatment Of Mucositis | POLYMEDIX, INC. | 2019-09-19 | — | — | US | disclosed |
| US-10206894-B2 | Compounds for use in treatment of mucositis | INNOVATION PHARMACEUTICALS INC. (US) | 2019-02-19 | — | — | US | disclosed |
| US-20180064664-A1 | Compounds For Use In Treatment of Mucositis | POLYMEDIX, INC. | 2018-03-08 | — | — | US | disclosed |
| US-9795575-B2 | Compounds for use in treatment of mucositis | INNOVATION PHARMACEUTICALS INC. (US) | 2017-10-24 | — | — | US | disclosed |
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |
| US-20170224640-A1 | Compounds For Use In Treatment Of Mucositis | INNOVATION PHARMACEUTICALS INC. | 2017-08-10 | — | — | US | disclosed |
| US-9457027-B2 | Compounds for use in treatment of mucostis | CELLCEUTIX CORPORATION (US) | 2016-10-04 | — | — | US | disclosed |
| WO-2016133733-A1 | HOST DEFENSE PROTEIN (HDP) MIMETICS FOR PROPHYLAXIS AND/OR TREATMENT OF INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT | CELLCEUTIX CORPORATION (US) | 2016-08-25 | — | — | WO | disclosed |
| US-20160243117-A1 | Host Defense Protein (HDP) Mimetics For Prophylaxis And/Or Treatment Of Inflammatory Diseases Of The Gastrointestinal Tract | CELLCEUTIX CORPORATION (US) | 2016-08-25 | — | — | US | disclosed |
| US-9155738-B2 | Compounds for use in treatment of mucostitis | CELLCEUTIX CORPORATION (US) | 2015-10-13 | — | — | US | disclosed |
| US-20150197485-A1 | Processes For Preparing A Polymeric Compound | CELLCEUTIX CORP (US) | 2015-07-16 | — | — | US | disclosed |
| US-8946475-B2 | Processes for preparing a polymeric compound | CELLCEUTIX CORPORATION (US) | 2015-02-03 | — | — | US | disclosed |
| US-20140364364-A1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | INNOVATION PHARMACEUTICALS INC. | 2014-12-11 | — | — | US | disclosed |
| US-8802683-B2 | Compounds for use in treatment of mucositis | CELLCEUTIX CORPORATION (US) | 2014-08-12 | — | — | US | disclosed |
| US-20130274502-A1 | Processes For Preparing A Polymeric Compound | POLYMEDIX, INC. (US) | 2013-10-17 | — | — | US | disclosed |
| US-20120295922-A1 | Compounds For Use In Treatment Of Mucositis | POLYMEDIX, INC. (US) | 2012-11-22 | — | — | US | disclosed |
| US-20110178104-A1 | Anti-Heparin Compounds | POLYMEDIX INC. (US) | 2011-07-21 | — | — | US | disclosed |
| WO-2011084970-A1 | ANTI-HEPARIN COMPOUNDS | POLYMEDIX INC. (US) | 2011-07-14 | — | — | WO | disclosed |
| WO-2011050162-A1 | PROCESSES FOR PREPARING A POLYMERIC COMPOUND | POLYMEDIX, INC. (US) | 2011-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170224640-A1 | Compounds For Use In Treatment Of Mucositis | MUC1, FUT6, MMP8 | KLK7 1583/4885KLK5 954/4885MAPT 4736/4885 |
| US-10603294-B2 | Compounds for use in treatment of mucositis | MUC1, FUT6, MMP8 | KLK7 1583/4885KLK5 954/4885MAPT 4736/4885 |
| US-20140364364-A1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | MUC1, FUT6, MMP8 | KLK7 1583/4885KLK5 954/4885MAPT 4736/4885 |
| US-20120295922-A1 | Compounds For Use In Treatment Of Mucositis | MUC1, FUT6, MMP8 | KLK7 1583/4885KLK5 954/4885MAPT 4736/4885 |
| US-20150197485-A1 | Processes For Preparing A Polymeric Compound | F12, ALG1, ABCB11 | KLK7 764/4885KLK5 359/4885MAPT 2243/4885 |
| US-20160243117-A1 | Host Defense Protein (HDP) Mimetics For Prophylaxis And/Or Treatment Of Inflammatory Diseases Of The Gastrointestinal Tract | FABP2, HMGB1, MASP2 | KLK7 2672/4885KLK5 2659/4885MAPT 4232/4885 |
| US-10206894-B2 | Compounds for use in treatment of mucositis | MUC1, FUT6, SI | KLK7 1969/4885KLK5 987/4885MAPT 4558/4885 |
| US-20110178104-A1 | Anti-Heparin Compounds | SERPINC1, CFH, SERPINH1 | KLK7 420/4885KLK5 215/4885MAPT 4851/4885 |
| US-20190282521-A1 | Compounds For Use In Treatment Of Mucositis | MUC1, FUT6, MMP8 | KLK7 1583/4885KLK5 954/4885MAPT 4736/4885 |
| US-20180064664-A1 | Compounds For Use In Treatment of Mucositis | MUC1, FUT6, SI | KLK7 1969/4885KLK5 987/4885MAPT 4558/4885 |
| US-20130274502-A1 | Processes For Preparing A Polymeric Compound | F12, ALG1, ABCB11 | KLK7 764/4885KLK5 359/4885MAPT 2243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.