Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15071683 | 0.83 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1L3MBTL1CYP2D6 | |
| SCHEMBL6536312 | 0.83 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1L3MBTL1CYP2D6 | |
| SCHEMBL31210789 | 0.83 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1L3MBTL1CYP2D6 | |
| SCHEMBL15071539 | 0.83 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1L3MBTL1CYP2D6 | |
| SCHEMBL4274767 | 0.83 | L3MBTL1 (0.68) | ALDH1A1KMT2AMEN1L3MBTL1CYP2D6 | |
| SCHEMBL6997045 | 0.82 | ACHE (0.58) | ALDH1A1KMT2AMEN1L3MBTL1CYP2D6 | |
| SCHEMBL6997039 | 0.82 | ACHE (0.58) | ALDH1A1KMT2AMEN1L3MBTL1CYP2D6 | |
| SCHEMBL694189 | 0.81 | CHRM2 (0.62) | ALDH1A1KMT2AMEN1L3MBTL1CYP2D6 | |
| SCHEMBL16766586 | 0.81 | CHRM2 (0.62) | ALDH1A1KMT2AMEN1L3MBTL1CYP2D6 | |
| SCHEMBL16766562 | 0.81 | CHRM2 (0.62) | ALDH1A1KMT2AMEN1L3MBTL1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110160235-A1 | TRIAZOLYL TROPANE DERIVATIVES | CONCERT PHARMACEUTICALS, INC. (US) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160235-A1 | TRIAZOLYL TROPANE DERIVATIVES | CCR5, CXCR4, CXCR3 | ALDH1A1 2139/4885KMT2A 4488/4885MEN1 4492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.