Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29112390 | 0.78 | HSD11B1 (0.54) | HSD11B1ALDH1A1SMN1; SMN2HTTATM | |
| SCHEMBL24540861 | 0.78 | HSD11B1 (0.54) | HSD11B1ALDH1A1SMN1; SMN2HTTATM | |
| SCHEMBL29112392 | 0.78 | HSD11B1 (0.54) | HSD11B1ALDH1A1SMN1; SMN2HTTATM | |
| SCHEMBL29141636 | 0.77 | HSD11B1 (0.52) | HSD11B1ALDH1A1SMN1; SMN2HTTATM | |
| SCHEMBL3614438 | 0.75 | HSD11B1 (0.56) | HSD11B1ALDH1A1SMN1; SMN2HTTATM | |
| SCHEMBL15649538 | 0.73 | HSD11B1 (0.54) | HSD11B1ALDH1A1SMN1; SMN2HTTATM | |
| SCHEMBL3457775 | 0.70 | HSD11B1 (0.42) | HSD11B1ALDH1A1SMN1; SMN2HTTATM | |
| Monoethanolamine SCHEMBL15918951 | 0.70 | HSD11B1 (0.50) | HSD11B1ALDH1A1SMN1; SMN2HTTATM | |
| SCHEMBL21003258 | 0.69 | ALOX5AP (0.48) | HSD11B1ALDH1A1SMN1; SMN2HTTATM | |
| SCHEMBL1159800 | 0.69 | TRPM8 (0.52) | HSD11B1ALDH1A1SMN1; SMN2HTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162018-B1 | SALT ENHANCEMENT | GIVAUDAN SA (CH) | 2012-10-17 | — | — | EP | claimed |
| US-7880011-B2 | reacting p-menthanecarboxamide in toluene with 2-vinyl pyridine, 18-crown-6 chelating agent , potassium tert-butoxide (20% in tetrahydrofuran), heating to produce N-(2-pyridin-2-ylethyl)p-menthanecarboxamide[(1R,2S,5R)-2-isopropyl-5-methyl-N-(2-(pyridin-2-yl)ethyl)cyclohexanecarboxamide | Givandan, S.A. (CH) | 2011-02-01 | — | — | US | disclosed |
| US-20090030042-A1 | Amide Addition Reaction | GIVAUDAN, SA. (CH) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030042-A1 | Amide Addition Reaction | HRH2, OGDH, MDH2 | HSD11B1 2015/4885ALDH1A1 2457/4885SMN1; SMN2 4003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.