Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3625830 | 1.00 | KMT2A (0.32) | KMT2AMEN1PAX8RAPGEF4HSP90AA1 | |
| SCHEMBL31013359 | 0.99 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1NPC1 | |
| Hydrochloric Acid SCHEMBL3625061 | 0.97 | KMT2A (0.32) | KMT2AMEN1PAX8RAPGEF4HSP90AA1 | |
| SCHEMBL1120699 | 0.97 | KMT2A (0.33) | KMT2AMEN1PAX8RAPGEF4HSP90AA1 | |
| SCHEMBL1120701 | 0.97 | KMT2A (0.33) | KMT2AMEN1PAX8RAPGEF4HSP90AA1 | |
| SCHEMBL29558324 | 0.97 | KMT2A (0.33) | KMT2AMEN1PAX8RAPGEF4HSP90AA1 | |
| SCHEMBL16654076 | 0.96 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1NPC1 | |
| SCHEMBL4531344 | 0.96 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1NPC1 | |
| SCHEMBL4531342 | 0.96 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1NPC1 | |
| SCHEMBL9952467 | 0.96 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210016265-A1 | Mixed Catalyst System | EXXONMOBIL CHEMICAL PATENTS INC. | 2021-01-21 | — | — | US | claimed |
| US-9676971-B2 | Systems, methods and compositions for production of tie-layer adhesives | EQUISTAR CHEMICALS, LP (US) | 2017-06-13 | — | — | US | claimed |
| US-20160222257-A1 | SYSTEMS, METHODS AND COMPOSITIONS FOR PRODUCTION OF TIE-LAYER ADHESIVES | EQUISTAR CHEMICALS, LP (US) | 2016-08-04 | — | — | US | claimed |
| US-8618228-B2 | Process for the preparation of ethylene copolymer compositions in the presence of an oligomerization catalyst | BASELL POLYOLEFINE GMBH (DE) | 2013-12-31 | — | — | US | claimed |
| US-20130085221-A1 | SYSTEMS, METHODS AND COMPOSITIONS FOR PRODUCTION OF TIE-LAYER ADHESIVES | EQUISTAR CHEMICALS, LP (US) | 2013-04-04 | — | — | US | claimed |
| US-12600844-B2 | Linear low density polyethylene for film applications | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2026-04-14 | — | — | US | disclosed |
| US-12577334-B2 | Broad orthogonal distribution polyethylenes for films | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2026-03-17 | — | — | US | disclosed |
| US-12534582-B2 | Linear low density polyethylene for film applications | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2026-01-27 | — | — | US | disclosed |
| US-12415911-B2 | Polyethylene composition for filaments or fibers | BASELL POLYOLEFINE GMBH (DE) | 2025-09-16 | — | — | US | disclosed |
| EP-4077422-B1 | BROAD ORTHOGONAL DISTRIBUTION POLYETHYLENES FOR FILMS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2025-09-10 | — | — | EP | disclosed |
| US-11999839-B2 | Polyethylene composition for filaments or fibers | BASELL POLYOLEFINE GMBH (DE) | 2024-06-04 | — | — | US | disclosed |
| EP-4069775-B1 | POLYETHYLENE COMPOSITION FOR FILAMENTS OR FIBERS | BASELL POLYOLEFINE GMBH (DE) | 2024-04-03 | — | — | EP | disclosed |
| US-20110130527-A1 | METHOD FOR TRANSITIONING BETWEEN INCOMPATIBLE OLEFIN POLYMERIZATION CATALYST SYSTEMS | BASELL POLYOLEFINE GMBH (DE) | 2011-06-02 | — | — | US | disclosed |
| US-20110045295-A1 | ADHESIVE POLYMER COMPOSITION | BASELL POLYOLEFINE GMBH (DE) | 2011-02-24 | — | — | US | disclosed |
| EP-2236577-A2 | Polyethylene composition | Basell Polyolefine GmbH (DE) | 2010-10-06 | — | — | EP | disclosed |
| US-7723448-B2 | Hybrid catalyst systems supported on magnesium halide | BASELL POLYOLEFINE GMBH (DE) | 2010-05-25 | — | — | US | disclosed |
| US-20100099825-A1 | Hybrid catalyst composition for polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2010-04-22 | — | — | US | disclosed |
| EP-2177543-A1 | Hybrid catalyst composition for polymerization of olefins | Basell Polyolefine GmbH (DE) | 2010-04-21 | — | — | EP | disclosed |
| US-20100093953-A1 | POLYETHYLENE, PROCESS AND CATALYST COMPOSITION FOR THE PREPARATION THEREOF | BASELL POLYOLEFINE GMBH (DE) | 2010-04-15 | — | — | US | disclosed |
| US-20090118445-A1 | Hybrid Catalyst Systems Supported On Magnesium Halide | BASELL POLYOLOLINE GMBH (DE) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12577334-B2 | Broad orthogonal distribution polyethylenes for films | CDR2, LBR, FCER2 | KMT2A 3239/4885MEN1 2239/4885PAX8 1413/4885 |
| US-12534582-B2 | Linear low density polyethylene for film applications | MIF, RPS2, RPS8 | KMT2A 3369/4885MEN1 3880/4885PAX8 1968/4885 |
| US-12600844-B2 | Linear low density polyethylene for film applications | RPS2, RPSA, LBR | KMT2A 2276/4885MEN1 4864/4885PAX8 3070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.