Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14167164 | 0.98 | P2RX7 (0.43) | P2RX7ESR1ESR2MAPTHSD17B10 | |
| SCHEMBL14764970 | 0.85 | L3MBTL1 (0.46) | MAPTALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL7405623 | 0.84 | P2RX7 (0.44) | P2RX7ESR1ESR2MAPTHSD17B10 | |
| SCHEMBL158861 | 0.83 | CTBP2 (0.55) | MAPTALDH1A1GAAPTGS2CTBP2 | |
| SCHEMBL29718576 | 0.83 | CTBP2 (0.55) | MAPTALDH1A1GAAPTGS2CTBP2 | |
| SCHEMBL6990892 | 0.82 | ALDH1A1 (0.48) | MAPTHSD17B10ALDH1A1GAAPTGS2 | |
| SCHEMBL4100411 | 0.82 | CYP3A4 (0.48) | ESR1HSD17B10ALDH1A1GAANPSR1 | |
| SCHEMBL5210376 | 0.82 | GAA (0.50) | MAPTHSD17B10ALDH1A1MAPK1GAA | |
| SCHEMBL228994 | 0.82 | PTGS2 (0.57) | ESR1ESR2MAPTGLASTING1 | |
| SCHEMBL7120045 | 0.82 | HTT (0.38) | HSD17B10ALDH1A1GAANPSR1ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703990-B2 | Process for manufacture and resolution of 2-acylamino-3-diphenylpropanoic acid | Zhejiang Jiuzhous Pharmaceutical Co., Ltd. (CN) | 2014-04-22 | — | — | US | claimed |
| US-20010021791-A1 | Novel intermediates useful for the preparation of antihistaminic piperidine derivatives | MERRELL PHARMACEUTICALS INC. | 2001-09-13 | — | — | US | claimed |
| JP-H08512028-A | — | — | 1996-12-17 | — | — | JP | claimed |
| EP-0705245-A1 | NOVEL INTERMEDIATES FOR THE PREPARATION OF ANTIHISTAMINIC 4-DIPHENYLMETHYL/DIPHENYLMETHOXY PIPERIDINE DERIVATIVES | MERRELL PHARMACEUTICALS INC. (US) | 1996-04-10 | — | — | EP | claimed |
| WO-1995000480-A1 | NOVEL INTERMEDIATES FOR THE PREPARATION OF ANTIHISTAMINIC 4-DIPHENYLMETHYL/DIPHENYLMETHOXY PIPERIDINE DERIVATIVES | MERRELL PHARMACEUTICALS INC. (US) | 1995-01-05 | — | — | WO | claimed |
| JP-59051207-A | — | — | None | — | — | JP | disclosed |
| EP-3639914-B1 | POLYMERIC MEMBRANES WITH HUMAN SKIN LIKE PERMEABILITY PROPERTIES AND USES THEREOF | EMD MILLIPORE CORP (US) | 2023-12-27 | — | — | EP | disclosed |
| US-11209421-B2 | Cytidine deaminase expression level in cancer as a new therapeutic target | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-12-28 | — | — | US | disclosed |
| US-11155517-B2 | 4-substituted phenylamine derivatives and their use to protect crops by fighting undesired phytopathogenic micoorganisms | PI INDUSTRIES LTD. (IN) | 2021-10-26 | — | — | US | disclosed |
| EP-3639914-A1 | POLYMERIC MEMBRANES WITH HUMAN SKIN LIKE PERMEABILITY PROPERTIES AND USES THEREOF | EMD Millipore Corporation (US) | 2020-04-22 | — | — | EP | disclosed |
| US-20190293629-A1 | CYTIDINE DEAMINASE EXPRESSION LEVEL IN CANCER AS A NEW THERAPEUTIC TARGET | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-09-26 | — | — | US | disclosed |
| EP-2555857-B1 | POLYMERIC MEMBRANES WITH HUMAN SKIN LIKE PERMEABILITY PROPERTIES AND USES THEREOF | EMD MILLIPORE CORP (US) | 2019-08-21 | — | — | EP | disclosed |
| US-6441179-B1 | FOR PRODUCING ANTIALLERGY AGENTS AND BRONCHODILATORS | MERRELL PHARMACEUTICALS INC. | 2002-08-27 | — | — | US | disclosed |
| US-20020077482-A1 | Novel intermediates useful for the preparation of antihistaminic piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. | 2002-06-20 | — | — | US | disclosed |
| EP-0813525-A1 | BENZAMIDINE DERIVATIVES THEIR PREPARATION AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1997-12-29 | — | — | EP | disclosed |
| WO-1996028427-A1 | BENZAMIDINE DERIVATIVES THEIR PREPARATION AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1996-09-19 | — | — | WO | disclosed |
| EP-0705245-A1 | NOVEL INTERMEDIATES FOR THE PREPARATION OF ANTIHISTAMINIC 4-DIPHENYLMETHYL/DIPHENYLMETHOXY PIPERIDINE DERIVATIVES | MERRELL PHARMACEUTICALS INC. (US) | 1996-04-10 | — | — | EP | disclosed |
| EP-0700387-A1 | SALTS OF SUBSTITUTED HETEROAROMATIC NITROGEN COMPOUNDS, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOUNDS CONTAINING SAME | SANOFI (FR) | 1996-03-13 | — | — | EP | disclosed |
| WO-1995000480-A1 | NOVEL INTERMEDIATES FOR THE PREPARATION OF ANTIHISTAMINIC 4-DIPHENYLMETHYL/DIPHENYLMETHOXY PIPERIDINE DERIVATIVES | MERRELL PHARMACEUTICALS INC. (US) | 1995-01-05 | — | — | WO | disclosed |
| JP-S5951207-A | HERBICIDE FOR PADDY FIELD | YASHIMA CHEM IND CO LTD | 1984-03-24 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11155517-B2 | 4-substituted phenylamine derivatives and their use to protect crops by fighting undesired phytopathogenic micoorganisms | PNMT, PAH, GNMT | P2RX7 607/4885ESR1 4649/4885ESR2 4639/4885 |
| US-20010021791-A1 | Novel intermediates useful for the preparation of antihistaminic piperidine derivatives | HRH1, HRH3, HRH4 | P2RX7 447/4885ESR1 3791/4885ESR2 2193/4885 |
| US-20020077482-A1 | Novel intermediates useful for the preparation of antihistaminic piperidine derivatives | HRH1, HRH3, HRH4 | P2RX7 544/4885ESR1 4122/4885ESR2 2680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.