Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 5/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 5/20 | 0.32 |
| ▸ | CDK1 | P06493 | 5/20 | 0.32 |
| ▸ | CDK4 | P11802 | 5/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.32 |
| ▸ | CCND1 | P24385 | 5/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.32 |
| ▸ | CDK2 | P24941 | 5/20 | 0.32 |
| ▸ | CCND2 | P30279 | 5/20 | 0.32 |
| ▸ | CCND3 | P30281 | 5/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.32 |
| ▸ | HTR1A | P08908 | 6/20 | 0.31 |
| ▸ | HTR1D | P28221 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13242468 | 0.72 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL13592867 | 0.70 | HTR1A (0.50) | HTR1AHTR1DHTR1BCYP1A2CYP2D6 | |
| SCHEMBL12874846 | 0.70 | THRB (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL12596193 | 0.68 | GRIN2D (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL13088151 | 0.65 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL12056204 | 0.64 | GRIN2D (0.41) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL12595701 | 0.64 | MTNR1A (0.37) | — | |
| SCHEMBL13592866 | 0.64 | CCNE2 (0.37) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL12596320 | 0.62 | CCNB2 (0.39) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL28694786 | 0.62 | PLA2G2A (0.38) | MAPTCYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110144090-A1 | COMPOUNDS AND METHODS OF USE THEREOF | GALENEA CORPORATION | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144090-A1 | COMPOUNDS AND METHODS OF USE THEREOF | AANAT, HNMT, INMT | GRIN2D 2417/4885GRIN3B 899/4885GRIN1 2100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.